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Articles by S.A. Khan
Total Records ( 3 ) for S.A. Khan
  C.P. Kumar , B.A. John , S.A. Khan , P.S. Lyla and A.S. Kamaleson
  Recent emergence of Chikungunya virus has attracted the researchers to explore its whole genome to predict the structural changes at the genetic level during disease outbreak. Present study was aimed to investigate the mutational patterns at the genome level in Chikungunya virus using advanced software programs. Pair-wise analysis of whole genome (n = 84) of Chikungunya virus revealed that structural genes mutated 2.6 times higher than non-structural genes. The chronological analysis showed that the Chikungunya virus prevalent during 2008 mutated higher than any other outbreaks recorded so far. Number of singleton sites in the variable region of viral genome was found higher when compared to number of parsimonous sites. Chronological and geographical scale analysis of the viral outbreak showed that about 30% of viral genome was subjected to mutation so far. Chikungunya virus isolated from Malaysian geography had underwent more mutations when compared anyother geographical locations. Highest number of singleton mutations were observed in Chikungunya viruses isolated from Malayasian geography whereas highest number of parsimonous informative sites were observed in Chikungunya isolates of India. The mutational analysis also revealed that viral genome contained two times more singleton sites compared to parsimonious sites. About 1207 nucleotides in the structural protein coding region of Chikungunya virus genome was identified as a unique DNA signature witch could be used in precise and fast diagnosing of Chikungunya virus in future.
  K. Kadharsha , P. Mohanchander , P.S. Lyla and S.A. Khan
  The feeding biology, spawning season, size at first maturity, sex ratio and fecundity of the commercially important lizardfish (Saurida undosquamis) were studied in Parangipettai waters of the southeast coast of India. Fishes formed the predominant food item. Diversity of the prey items showed maximum value (H’log 2-3.61±0.11) during the postmonsoon season and minimum during the monsoon season (2.89±0.17). The richness (1-lambda’) also showed a similar trend and varied from 0.81±0.13 (monsoon) to 0.91±0.01 (postmonsoon). The size at first maturity (50% incidence of mature fish) was 195 mm. But when the size at first maturity was calculated by adjusting the proportion of maturity percentages, the maturity size was found to be 140 mm. This method is advantageous from the point of view of fisheries management as this species can be exploited above 140 mm rather than above 195 mm. The gastrosomatic index was found maximum during postmonsoon and minimum during the monsoon season showing the inverse relationship between feeding and spawning. This species was found to spawn from August to January with a peak in November. The fecundity ranged from 19, 856 in a fish measuring from 20.1 cm in length (97 g) to 79,282 in a fish of 29 cm (290 g). The overall sex ratio (1:1.19) was found to deviate significantly from the expected 1:1 ratio. (χ2 = 19.1, p<0.005). Month- wise, it conformed to the expected 1:1 ratio during most of the months except January, June, September, November and December. Higher gonado-somatic index values observed during October-December suggested spawning activity during this period. This species is found to a total spawner in the Parangipettai waters.
  M. Mushtaq , N.A. Shah , G. Muhammad , S.A. Khan , S. Ari and Y.N. Anjam
  In this study, the Direct Boundary Element Method (DBEM) is being applied to present solution for surface and ground water bodies which are important nutrition fluids. To calculate a steady, irrotational, inviscid compressible flow past a Joukowski aerofoil using Direct Boundary Element Method with linear element approach. The results obtained using this method has been compared with the analytical solutions for the body under consideration.
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