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Articles by S. Srivastava
Total Records ( 5 ) for S. Srivastava
  R. Kumar , A. Sinha , S. Srivastava and M. Srivastava
  The aim of the present study was to investigate the variation in soil mycobiota involved in the decomposition of Sesbania aculeata L. in soil. Decomposition of Sesbania aculeata (Dhaincha) was studied by nylon net bag technique under experimental conditions. The colonization pattern by soil inhabiting mycobiota was studied by standard methods. Among the three methods used for isolation and enumeration of fungi, dilution plate technique recorded the highest number of fungi followed by damp chamber and direct observation method. Nutrient availability and climatic conditions influenced occurrence and colonization pattern of mycobiota. Maximum fungal population was recorded in July (48.95±0.20x104 of fungi/g oven dry litter) and minimum in June (19.78±0.20x104 of fungi/g oven dry litter). The distribution of Deuteromycetous fungi was much more (74.47%) than Zygomycetes, Oomycetes and Ascomycetes. In the early stage of decomposition Mucor racemosus, Rhizopus stolonifer, Chaetomium globosum and Gliocladium roseum were found where as at the later stages of decomposition preponderance of Aspergillus candidus, Cladosporium cladosporioides, Curvularia lunata and Aspergillus luchuensis was recorded.
  S. Srivastava , V.P. Singh , R. Kumar , M. Srivastava , A. Sinha and S. Simon
  The aim of the present study was to check the efficacy of carbendazim 50% WP, antagonists and botanicals against Fusarium oxysporum f. sp. psidii associated with rhizosphere soil of guava. Guava (Psidium guajava L.) the apple of tropics is one of the most important fruit in India. The fruit of guava is a good source of vitamin C and pectin. Guava wilt is a serious disease and it recognized as a main causal organism. Isolation and identification of pathogen (Fusarium oxysporum f. sp. psidii) was carried out in the Department of Plant Protection, Allahabad Agricultural institute Deemed University, Allahabad. The radial growth of Fusarium cxysporum f. sp. psidii was fully inhibited at high concentrations like 100, 1000 and 10,000 ppm of cardendazim 50% WP whereas antagonists like Trichoderma spp. Produced maximum inhibition zone (61.91%) followed by Aspergillus niger (61.12%). The radial growth of Fusarium cxysporum f. sp. psidii was also significantly less in neem leaf extract treatment followed by Lantana leaf extract. Management of guava wilt by chemical (systemic fungicide) can be spectacular but this is relatively short-term measure. Eco-friendly management practices, i.e., use of bio-control agents and botanicals was studied in vitro which gave better results and these practices can be economical, long lasting and free from residual side effects.
  W Wang and S. Srivastava

Although the potential of biomarkers to aid in the early detection, diagnosis, prevention, and treatment of breast cancer is broadly recognized and numerous biomarker candidates have been reported in the literature, few molecular markers have been adopted into clinical use to date. To address this lack of translation of biomarkers from the bench to clinical practice, the Cancer Biomarkers Research Group in the Division of Cancer Prevention of the National Cancer Institute organized a meeting, "Strategic Discussion on Biomarkers for Breast Cancer," which was held at the Fred Hutchinson Cancer Research Center on September 14, 2008. Participants included industry leaders, basic and physician scientists, and National Cancer Institute program staff. The objectives of this strategic discussion were to define clinical uses and needed performance characteristics of biomarkers; to identify novel approaches to discover and validate breast cancer biomarkers, particularly those with improved chances of being clinically useful; and to identify candidate DNA methylation markers that could be taken forward for validation. Participants presented and recommended methylation biomarkers suitable for initiating collaborative projects to evaluate the markers for future clinical application. This commentary summarizes their discussions and recommendations and the rationale for initiating specific projects to validate DNA methylation biomarkers of breast cancer. Cancer Prev Res; 3(1); 16–24

  B. Dhir , S.A. Nasim , S. Samantary and S. Srivastava
  Accumulation of osmolytes in terrestrial plants in response to environmental stresses is well reported and information about aquatic plants is limited. Present study aimed to investigate if the aquatic weed, Salvinia natans accumulates osmolytes/compatible solutes on exposure to various heavy metals. Plants exposed to heavy metals viz. Cd, Cu, Ni, Cr, Mn, Fe, Co, Pb and Zn, were harvested after 48 h and various osmolytes including sucrose, mannitol, proline, glycine betaine and polyamines were estimated using biochemical methods. Results suggested that heavy metal stress does trigger the accumulation of osmolytes such as sucrose, mannitol and glycine betaine. In contrast proline accumulation was not observed. Studies of heavy metal stress on the endogenous levels of polyamines showed presence of free polyamines, while conjugated and bound forms were not detected. Among free polyamines, Putrescine (Put) and Spermidine (Spd) did not show significant decrease in heavy metal exposed Salvinia except Pb and Fe exposed plants. Spermine (Spm) content showed decline in heavy metal exposed Salvinia. The decrease in polyamine levels indicated their possible role in combating oxidative stress induced by heavy metals. Studies suggest that accumulation of osmolytes under heavy metal stress might help in imparting tolerance in Salvinia.
  B. Dhir , S.A. Nasim , S. Nafees and S. Srivastava
  In the present investigation, tomato plants irrigated with treated wastewater were evaluated for their toxicity using short term (acute) animal studies. Male wistar rats fed with tomato plants at the dosage of 150 and 300 mg kg–1 b.wt. for 14 consecutive days showed no symptoms of toxicity. Assessment of haematological parameters such as RBC, WBC, haemoglobin, platelet count showed no significant changes. Plasma and serum analysis also indicated no significant differences in parameters such as urea, AST, ALT, ALP, bilirubin in all the treatments. The present investigations suggested that short term wastewater irrigation in plants do not pose any toxicity to animals. The toxicity depends upon the level of composition of treated wastewater and its transfer to the soil and then plants. Further studies are required to assess toxic effect of long term irrigation with treated wastewater.
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