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Articles by S. Siddiqui
Total Records ( 2 ) for S. Siddiqui
  Eman Atito , Mahmoud F. Moustafa , S. Siddiqui and Magdi El-Sayed
  Background and Objectives: Doum (Hyphaene thebaica) is a common palm tree in Egypt and produce an edible fresh fruits or dried in refreshment drinks. Another relative desert uncommon palm, Argun (Medemia argun) deserves extra focus as its fruits were found reserved in Pharaohs tombs. This study is designated to examine the phytochemicals, nutrient content, antioxidant and antimicrobial inhibitions activities of fruit parts of H. thebaica (HT) and M. argun (MAR). Materials and Methods: The total phenolic and flavonoid contents of fruit parts (mesocarp (M), coat (C) and seed endocarp (E)) were investigated spectrophotometrically. Antioxidant properties were measured as total antioxidant capacity, DPPH and H2O2 scavenging. The nutritional values determined as carbohydrates, proteins contents and anti-α-amylase activities. A bioassay based on inhibition zone on agar plate was applied to evaluate the antibiotic activity of the HT and MAR metabolites against 4 pathogenic bacterial strains. Results: The results displayed that antioxidant, antibacterial activities and nutritional values differ significantly in the endocarp, mesocarp and coat samples of both fruits. Flavonoids and phenolics content are high in endocarp of each fruit and low in mesocarp. Total phenolics from fruits parts ranged between 40.65-327.48 mg GAE g1 of dry sample. The IC50 values for radical scavenging of DPPH of MARE, MARM, MARC, HTE, HTM and HTC were 55.01, >500, 293.36, 53.76, >500 and 137.89 μg mL1, respectively. The hydrogen peroxide scavenging efficacy of the various extracts obtained from HT and MAR was in the order of HTE>MARE>MARC>HTC>HTM>MARM. IC50 inhibitory activity of α-amylase showed the maximum in HT mesocarp, followed by HT coat and HT endocarp. At the concentrations of 100, 200, 300, 400 and 500 μg mL1, HT mesocarp (HTM) showed inhibitory activity of 61.57, 85.67, 86.93, 83.97 and 85.20%, respectively and while MAR mesocarp (MARM) was 60.67, 64.13, 83.83, 82.23 and 82.27%, respectively. HTE and MARE extracts possess potential antioxidant and antibacterial properties followed by HT coat (HTC) and MAR coat (MARC). Conclusion: Argun fruit has strong biological activities similar to doum fruits and potentially can be used as food dietary supplement to cure cancer and diabetic diseases.
  Hina Syed , K.M. Khan , K. Rehman and S. Siddiqui
  Air pollution is caused by the increased concentration of any of its constituent above the normal value and this type of situation prevails in highly industrialized areas. SO2 is among the air pollutants which produces bad effects on human health. The value of IgG in industrial workers were high and IgM was low which might be due to repeated exposure to SO2 pollutant, IgM production was switched over to IgG which results in high level of IgG and low level of IgM. IgA level was low, which might be due to the transportation of circulatory lgA to the epithelial surface for defence.
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