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Articles by S. Sarahroodi
Total Records ( 7 ) for S. Sarahroodi
  S. Sarahroodi , A. Arzi , A.F. Sawalha and A. Ashtarinezhad
  The aim of this study is to evaluate the knowledge and behavior toward antibiotic self-medication among medical and non-medical university students in Iran. A cross-sectional study was conducted on a sample of 200 students randomly chosen from a medical and a non-medical university in Ahwaz, South of Iran in 2008. Data was collected using self administered questionnaires with open-ended and close-ended items. Data were entered and analyzed using SPSS 14 and the results were presented as the percentage 97.5% of respondents filled and returned the questionnaire. Self-medication with antibiotics was reported by 42.2% of the medical and 48% of the non-medical students during the last 3 months. Respiratory problems such as sore throat and common cold was the main indication for self-medication with antibiotics (73.3%) and amoxicillin was the most commonly used antibiotic in both groups. The choice of self-medication was based on medical knowledge among medical students (50%) and on a previous suggestion by a physician (32.6%) for the non-medical ones. The prevalence of self-medication with antibiotics among medical and non-medical students was high. Educational programs are needed to teach university students about the potential problems of self-medication with antibiotics.
  S. Sarahroodi and A. Arzi
  The aim of the present study was to evaluate the knowledge and behavior toward antibiotic self-medication among college students in the capital of Iran (Tehran). A close and open-ended questionnaire was used to collect data from a sample of 160 students, randomly chosen from Shariaty Technical Faculty, Tehran, Iran. Data was collected using self administered questionnaires with open-ended and close-ended items. Data were entered and analyzed using SPSS 14 and the results were presented as the percentage. About 97.5% of respondents filled and returned the questionnaire. Self-medication with antibiotics was reported by 53% of students during the last 3 months. The main indication for self-medication with antibiotics was respiratory problems (73.3%) such as common cold and sore throat. Amoxicillin was the most commonly used antibiotic (40%). The main source of medicines was drugs which stored in students home (47.8%) and after that drugstores (44.8%). Only 26.8% of antibiotic users completed the course of antibiotic therapy. The prevalence of self-medication with antibiotics among college students was high. Educational programs are needed to teach university students about the potential problems of self-medication with antibiotics.
  A. Arzi , S. Sarahroodi , M. Mehrabizadeh Honarmand , S. Jamshidi and M. Latifi
  Diltiazem (DTZ) is widely used in the prophylaxis of hypertension and treatment of angina. The effects of DTZ and other calcium channel blockers on memory have been discussed with several procedures and different theories have been suggested. In the present study, the effect of DTZ on retention and retrieval of memory in young and aged mice was investigated by using the passive avoidance apparatus. For this purpose, after weighting, coding and classifying the mice, they were grouped as follow: test group received electric shock plus DTZ (10 and 30 mg kg-1, i.p.), blank group received electric shock plus normal saline and control group received only electric shock. In all three groups delay time of leaving the platform for both retention and retrieval test of memory was measured. DTZ was administered immediately after receiving electric shock in the retention test, but in retrieval test DTZ was administered 24 h after receiving electric shock. The results indicated that 30 mg kg-1 of DTZ impaired retention and retrieval of young mice memory. The 30 mg kg-1 of DTZ enhanced retention while 10 and 30 mg kg-1 of it improved retrieval of aged mice memory.
  A. Arzi , M. Ahamehe and S. Sarahroodi
  Epilepsy an important CNS (Central Nervous System) problem that about 1% f world’s population suffer of it. The aim of study was to evaluate of anticonvulsant effect of hydroalcoholic extract of Lavandula officinalis. In this study, anticonvulsant activity of the hydroalcoholic extract of Lavandula officinalis (L. officinalis) was studied against chemoconvulsant-induced seizures in male mice. Lavandula officinalis (100, 200, 400, 600 and 800 mg kg-1), diazepam (0.15 mg kg-1) and normal saline (10 mL kg-1) were injected intraperitoneally, respectively in different groups of mice, 30 min before nicotine (5 mg kg-1 i.p.). The onset time intensity and duration of convulsions and the percentage of death were recorded. Also the time-response (0, 15, 30, 45, 60 min before nicotine injection) for most effective dose of plant extract (600 mg kg-1) was investigated. The results showed that hydroalcoholic extract of Lavandula officinalis had anticonvulsant effect. The most effective dose of plant extract was 600 mg kg-1. In time-response study for the most effective dose of extract (600 mg kg-1), the onset, duration and intensity of convulsion significantly (p<0.05) increased, decreased and decreased, respectively for all tested times. The best response observed in 30, 45 and 60 min. The results showed significant anticonvulsant effect for hydroalcoholic extract of Lavandula.
  A. Arzi , F. Namjouyan , S. Sarahroodi , Z. Nazari Khorasgani and E. Macvandi
  Objective: Antinociceptive and anti-inflammatory activities of hydroalcoholic extract of Teucrium Oliverianum were investigated by formalin test model. This study was conducted in on the male Wistar rats, weighting 150-180 g. The animals were divided into seven groups (n = 7) and recieved 200, 400, 600 and 800 mg kg-1 of hydroalcoholic extract of teucrium oliverianum intraperitoneally, respectively. Negative control group received normal saline (5 mL kg-1) and the positive control groups received 2.5 mg kg-1 morphine and 300 mg kg-1 aspirin, intraperitoneally respectively. The results showed that all doses of extract have significant analgesic effect (p<0.05) in all studies times in comparison with negative control. The best result achieved with 600 mg kg-1 of extract. The result revealed that the analgesic effect of the extract (600 mg kg-1) \was less than aspirin (300 mg kg-1) on the second phase of pain and less than morphine (2.5 mg kg-1) in both phases of the pain, more than aspirin in first phase of pain. One group of animals was treated with naloxone (1 mg kg-1, i.p.) and suitable dose of extract (600 mg kg-1, i.p.). Also, Naloxone inhibited analgesic effect of alcoholic extract of Teucrium Oliverianum. It can be concluded that the alcoholic extract of Teucrium oliverianum may exert its effect through opioid receptors, stimulating GABAergic system or promotes the release of endogenous opipeptides or decreasing free radicals.
  S. Sarahroodi and P. Mikaili
  Not Available.
  S. Sarahroodi , R. Jafari-Najafi , S. Nasri , K. Rohampour , A. Maleki-Jamshid and S. Esmaeili
  There are several evidences that plants and vegetables with antioxidant activity can reduce oxidative damages in brain and improve cognitive functions. The aim of this study was evaluation of Nepeta menthoidesaqueous extract on memory retention and retrieval of mice by using passive avoidance apparatus. For this purpose, mice were classified, coded, weighted and grouped (n = 8) as follow as: control group (Only electric shock), blank group (electric shock plus normal saline) and test groups (electric shock plus Nepeta menthoides extract by doses: 100, 200, 400 and 800 mg kg-1, i.p.). Delay time of leaving the platform was measured for retention and retrieval test of memory in all mentioned groups. In retention test, plant extract was administered immediately after receiving electric shock while it was administered 24 h after receiving electric shock in retrieval. The results revealed that Nepeta menthoides aqueous extract significantly (p<0.05) increased memory retention and retrieval. The best response for memory retention and retrieval was achieved with 800 mg kg-1 of Nepeta extract. In conclusion, enhancement of memory retention and retrieval by Nepeta menthoides could be cause of antioxidant activity of its components such as rosmarinic acid, caffeic acid and phenolic acids.
 
 
 
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