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Articles by S. Saadat
Total Records ( 2 ) for S. Saadat
  S. Saadat , S. Sadeghian , R. Hamidian and M.A. Najafi
  This study is aimed to evaluate the impact of air pollution on the in-hospital mortality of ischemic heart disease patients in Tehran as a polluted metropolis. A cross sectional study conducted in Tehran heart center. We compared two separate exposure levels of air pollutants in patients expired in hospital (n = 23) versus patients discharged alive (n = 1219). The first was air pollutants daily mean concentration at the date of admission and the second was air pollutants daily mean concentration at the date of admission and the three following days. Patients' demographic, clinical and paraclinical data were gathered from the hospital databank between 23 September and 21 December 2005. Meteorological data were obtained from Tehran air quality control company. In-hospital mortality rate was 1.9% for men and 1.8% for women. The expired patients were older than survived patients. The mean concentration of carbon monoxide, dust, nitrous oxide, other nitrogen compounds and sulfur dioxide were significantly higher and mean temperature was significantly lower at admission date of expired patients. In expired patients, mean concentrations of nitrous oxide, nitrogen dioxide, other nitrogen compounds, sulfur dioxide, dust and non-methane hydrocarbons were significantly higher at admission date and three following days compared to survived patients. There was significant direct relationship between air pollution level and in-hospital mortality of ischemic heart disease patients.
  H. Ravari , M.R. Zafarghandi , D. Alvandfar and S. Saadat
  This study was aimed to evaluate the association of serum homocysteine with peripheral atherosclerosis and deep vein thrombosis in an Iranian population complaining from vascular symptoms in lower limbs referred to a university general hospital in the capital of Iran. The study design was case-control. Deep vein thrombosis and atherosclerosis groups were, respectively consisted of 25 patients presenting with signs and symptoms of deep vein thrombosis whom disease was confirmed by duplex ultrasonography and 25 patients presenting with signs and symptoms of chronic arterial insufficiency who were candidate for arterial reconstruction whom disease was confirmed by angiography. The control group was consisted of 25 persons selected among relatives accompanying the traumatic patients admitted in the general surgery ward of the same hospital. The age of atherosclerosis, DVT and control group were 61±14, 47±16 and 40±14, respectively. The serum level of homocysteine was higher in males (p<0.01) except for atherosclerotic patients. The prevalence of high homocysteine was 15% (control), 36% (DVT) and 56% (atherosclerosis) among females and 75% (control), 73% (DVT) and 56% (atherosclerosis) among males. The serum homocysteine in the control group which was representative of Tehran population who do not take vitamin B supplements was unexpectedly high. It seems that fortification of popular foodstuffs should be considered for Tehran. The association between homocysteine and atherosclerosis and deep vein thrombosis was not confirmed in this study especially for men who had higher serum homocysteine than women. It is possible that this association fades away in populations with high prevalence of hyperhomocysteinema.
 
 
 
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