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Articles by S. Rajasekaran
Total Records ( 4 ) for S. Rajasekaran
  S. Rajasekaran and V. Gopalakrishnan
  Induction motors are widely used in industries for obtaining motive power, as it has many practical advantages over other types of electrical motors. Induction motor characteristics are suited for Variable Speed Drive which is mostly preferred over Constant Speed Drive. This study implements speed control of two three-phase induction motors are controlled on the basis of FPGA drives. The SVPWM is criticized on a single FPGA chip to provide necessary switching pulses for inverter blocks .The adjustable speed is worked out bymanaging voltage and frequency using FPGA. The experimental setup is built with Xilinx Spartan-6 FPGA family. Experimental results are evidence for that FPGA-based solution for multi induction motor drives are operation flexibility, lower cost and good in performance.
  S.K. Uma Maheswaran , M. Meenakshi Sundaram and S. Rajasekaran
  Nosocomial infections or hospital acquired infections are diseases that develop during an admission to hospital and are a consequence of treatment, procedures of treatment or work of hospital staff. These infections are dangerous because they are caused by bacteria that are developed and transmitted within the hospital, where they may reach a high level of resistance to antibiotics. The goal of this study is to identify such infections for a single patient or hospital units and to create a real time information system for analyzing the microbiological data and to control the infections. In order to attain this objective, we introduce a knowledge based system approach for microbiological investigation to select the most suitable antibiotic therapy. The knowledge base of the proposed system has been obtained from international standard guidelines for microbiological laboratory practice, from experts’ suggestions. Also we present the overall structure of the system and its implementation. This system will help medical practitioners and physicians to adopt appropriate methodology for controlling nosocomial infections.
  R. Saravanan , K. Kumar Ebenezar , S. Rajasekaran and R. Thamaraiselvan
  The aim of the present study is to isolate the sulfated polysaccharides from marine macro algae S. wightii. The crude sulfated polysaccharides were fractionated by anionic resin (Amberlite IRA-900) and the separated active fractions were confirmed by agarose gel electrophoresis. The active fractions were pooled, dialyzed and purified by molecular sieve (Sephadex G-100) chromatography. The molecular weight of fractionated as well as purified sulfated polysaccharides was determined through gradient polyacrylamide gel electrophoresis (PAGE) and the disaccharide profile of purified sulfated polysaccharides was also analyzed. The structure of purified sulfated polysaccharides was dogged by 1H-NMR spectrum. The elements such as Carbon, Hydrogen and Nitrogen (CHN) and Activated Partial Thromboplastin Time (APTT) were observed from the purified sulfated polysaccharides. The hexosamine, uronic acid and the CHN content in the purified sulfated polysaccharides were found to be low (except molecular weight) when compared to standard heparan sulfate. The molecular weight of purified sulfated polysaccharides have 6,500 Da and the concentration of disaccharide profile such as 5.52% of uronic acid, 3.47% hexosamine and 5.4% of sulfate. APTT of fractionated and purified sulfated polysaccharides was found to be 24.6 and 31.1 IU mg-1, respectively. These results suggest that the sulfated polysaccharides from S. wightii could be an alternative source of anticoagulant.
  S. Rajasekaran and D. Sathishsekar
  Generalized abnormalities in glycoprotein metabolism are reported in both naturally occurring and experimental diabetes. The effect of Aloe vera, a traditionally used plant for the treatment of diabetes mellitus, was examined in Streptozotocin (STZ)-induced diabetic rats on derangement in glycoprotein’s levels. STZ injection (55 mg kg-1 body weight) caused massive alterations of glycoprotein components such as hexose, hexosamine and sialic acid in plasma and tissues (liver and kidney) of diabetic control and experimental groups of rats. Oral administration ethanolic extract of Aloe vera leaf gel extract (300 mg kg-1 body weight) for 21 days significantly restored the levels of hexose, hexosamine and sialic acid to near normalcy. These effects were compared with glibenclamide, a reference drug. Thus, the present study confirms that Aloe vera gel extract possesses a significant beneficial effect on glycoprotein components in STZ-induced diabetic rats, thereby preventing glycoprotein’s mediated secondary diabetic complications.
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