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Articles by S. Nikakhlagh
Total Records ( 5 ) for S. Nikakhlagh
  S. Nikakhlagh , F. Rahim , G. Saki , A. Khosravi , H. Rekabi and N. Saki
  The aim of this retrospective study was investigating the anatomical position and causes of deep neck infections as well as detection of the relation of these variables with age and gender of the patients. In this study, patient with primary deep neck infections referred to ear, nose and throat ward during 1998 to 2009, were studied. After definite diagnosis of infection in head and neck spaces, the exact infection-causing agent and its complications were reviewed. Furthermore, age and sex of patients, co-existing symptoms, bacterial culture results causing the infection, disease background, presence or absence of addiction reviewed and information obtained in the questionnaire were recorded. For comparison Chi-square test was used. The most common cause of deep neck infection, was dental infection in 130 patients [(49%); 78, male; 52, female] followed by tonsillar infection in 44 patients (16.6%). The deep neck infection space types: simultaneous spaces includes sub-mandibular, sub-mental, sub-lingual (Ludwig's angina) in 59 patients (45.4%), then sub-mandibular space in 54 patients (41.5 %) and para-pharyngeal space in 32 patients (24.6%) were more common. Bacterial culture were done only in 50 patients, of which, 28 cases of bacterial growth occurred. The most common organism was streptococcus viridians in 18 patients. The deep neck infections are dangerous and life-threatening that often occurs due to dental infections. Therefore, it seems that promote public knowledge about oral health, to increase the need of dental and treatment centers, timely cure and manage the infections, which play an important role in reducing the deep neck infections.
  S. Nikakhlagh , N. Saki , R.A. Baghbdrani , F. Rahim and A.F.Z. Sheikh
  This analysis aimed to resolve the qualitative and quantitative microbiology of adenoid tissue in children with or without recurrent otitis media. Total 133 children (aged 1-9 years) due to adenoid infection that underwent adenoidectomy in Imam Khomeini Hospital between Jan 2008 to Dec 2009, were engaged in this study. Of the 133 children studied, 67 (50.36%) patients with recurrent otitis media and 66 (49.62%) patients in the group without recurrent otitis media were observed. The most common organisms isolated were Alpha-hemolytic streptococci, Heamophilus influenzae and Streptococcus pneumoniae. All the organisms were sensitive to Ciprofloxacin. Alpha-hemolytic Streptococci were the most common types that were isolated from 31 (23.3%) patients with recurrent otitis media and from 27 (20.3%) patients without recurrent otitis media. Out of 66 cases without recurrent otitis media, Alpha-hemolytic Streptococci were more common in age groups of 2 to 3 years [9 patients (6.76%)] and age groups of 4 and 5 years [9 patients (6.76%)]. Of 67 patients with recurrent otitis media, Alpha-hemolytic Streptococci were observed more in age group 4 to 5 years [8 patients (6%)]. As the result, Gram negative bacteria revealed significant differences among patients with and without recurrent otitis media (p<0.001). This study shows that the incidence of tonsil bacterial infection in children with recurrent otitis media is higher than children without recurrent otitis media.
  A. Ebadi , N. Saki , S. Nikakhlagh and F. Rahim
  The aim of this study was to evaluate the hemodynamic effects of adenoidectomy under general anesthesia from May 2004 to August 2008. In this retrospective study, 747 patients from 1 to 15 years of age were scheduled underwent general anesthesia with mixture of thiopentone with atracurium, fentanyl and glucose-free solutions, for adenoidectomy surgery compatible with the technique. The following factors were assessed: age, ASA physical status, gender, preoperative, during operation and post-operative pulse rate. A total of 747 adenoidectomy were performed during the study period. One hundred and twenty three cases (16.46%) had bradycardia during adenoidectomy. More population were under 3 years old (49.55%) and males (76.7%). Out of 123 cases that developed bradycardia, 80 cases without need to atropine treatment and only 43 cases that need intravenous Atropine for control of it. Adenoidectomy is the most common operations performed in children under general anesthesia. Adenoidectomy related incidents were the most common cause and were more likely to occur during the maintenance phase of anesthesia, due to the vagal stimulation. Bradycardia due to surgery stimulation happened very early and patients were able to recover from the administration of atropine.
  S. Nikakhlagh , F. Rahim , A. Khodadadi and N. Saki
  The aimed to evaluate the plasma level of Viral Capsid Antigen (VCA)-IgA and IgG in family members of Nasopharyngeal Carcinoma (NPC) patient in comparison to healthy controls in Southwestern of Iran. Total 60 NPC patients were compared with 60 sex, age and ethnically matched healthy controls. The obtained serum samples participants were tested for VCA-IgA, VCA-IgG, Early Antigen (EA), IgG, EBNA-IgG by ELIZA. There was no significant difference in all EBV antibodies between patients and control groups (p>0.05). The serological of three IgG antibody meant that 66.6% of two groups had the past infection; of NPC families 6.6% and from controls 1.6% were susceptible to infection with EBV. 3.3% in members of NPC families had reactivation infection. The sex of the patients in case group had positive correlation with VCA-IgA, EBNA-IgG, EA-IgG and negative correlation with VCA-IgG. The age of the patients also showed positive correlation with EBNA-IgG, EA-IgG, VCA-IgG and negative correlation with VCA-IgA. None of the EBV antibodies had significant correlation with age and sex of the patients. Because of no statistical difference between VCA-IgA mean titr from members of NPC families and controls, there is the not higher risk for members of NPC families to controls for NPC. The cause that had positive VCA-IgA also had positive EBNA-IgG and VCA-IgG. Anti-EBV antibodies can be used as diagnostic markers of NPC in Southwestern region of Iran. The combined use of two or more markers marginally improved the discriminating power but that has to take into consideration the higher costs.
  S. Nikakhlagh , A.D. Khosravi , A. Fazlipour , M. Safarzadeh and N. Rashidi
  The aim of this study was to determine the microbiology of CSOM in patients diagnosed with chronic otitis media referred to Otorhinolaryngology Clinic. Samples for culture were taken from 50 patients with CSOM. The samples were cultured on enriched differential and selective media and kept in both aerobic and anaerobic conditions. Conventional biochemical tests were then performed on isolated colonies. Drug susceptibility testing was done according to standard protocol. Forty one (82%) of the middle ear cultures were positive. The most common isolated aerobe was Staphylococcus aureus (32.4%) followed by Pseudomonas aeruginosa (21.6%). In the anaerobic group (12%), the peptococcus species was most prevalent. The most effective antibiotic in the aerobic isolates was ofloxacin. According to the results of drug susceptibility test, 95.5% of strains including all the S. aureus isolates were sensitive to ofloxacin. The present study was one of the extensive reports on both aerobic and anaerobic bacteria in CSOM. Knowledge of the pathogens, responsible for CSOM and choose suitable antibiotics according to susceptibility tests should guide the management of disease treatment and reduces intracranial and extra cranial complications with CSOM.
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