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Articles by S. Dube
Total Records ( 4 ) for S. Dube
  S. Dube , I. Errazuriz , C. Cobelli , R. Basu and A. Basu
  Carbohydrate metabolism in humans is regulated by insulin secretion from pancreatic β-cells and glucose disposal by insulin-sensitive tissues. Insulin facilitates glucose utilization in peripheral tissues and suppresses hepatic glucose production. Any defects in insulin action predispose an individual to glucose intolerance and Type 2 diabetes mellitus. Early detection of defects in insulin action could provide opportunities to prevent or delay progression of the disease state. There are different approaches to assess insulin action. Initial methods, such as peripheral insulin concentration and simple indices, have several limitations. Subsequently, researchers developed methodologies using intravenous glucose infusion to determine glucose fluxes. However, these methodologies are limited by being non-physiological. Newer, innovative techniques that have been developed are more sophisticated and physiological. By modelling glucose kinetics using isotope dilution techniques, several robust parameters can be obtained that are physiologically relevant and sound. This brief review summarizes most of the non-physiological and physiological methodologies used to measure the variables of insulin action.
  S. Dube , E. Mwenje , K. Gora and C. Dube
  Two sets of 150 day old broiler chickens were fed with starter mesh for 14 and 21 days respectively and there after given grower mesh until day 35 after which both were fed on finisher until day 42. There was no significant difference in the final carcass mass of both (p>0.05). Another trial was set up to investigate the effect of application of probiotics as liquid and as powder on 2500 birds per treatment and a control with no probiotics was also set up. The results showed that probiotics applied as liquid had the best effect on PEF and FCR. The experiment to determine the best time to apply probiotics was conducted on 2000 birds per treatment. The results showed that the best performance was obtained when application of probiotics was started at 14 days The PEF was also highest on birds which started probiotics on day 14.
  S. Dube , E. Mwenje and E. Kambasha
  In this study we tested the effect of altering ostrich feed, by adding silage to feed in the ratio 2:1, by reducing feed levels to 90% and 75%, by adding antimicrobial growth promoter Zinc bacitricin and flavoumycin and presenting probiotics as liquid and powder. For each trial a control was set up with only normal prescribed feed supplied. All the birds used were health kept under high hygiene and vaccinated and dewormed to remove interference from pathogens. The results indicated that silage improved palatability and food intake. Reducing feed levels did not significantly alter the FCR or the performance of the birds. Growth promoters increased FCR but mortality was high. Probiotics were more effective when presented in liquid form than powder. The results show that data on effectiveness of feed supplements should be extrapolated to ostriches with caution.
  S. Dube , P. Zindi , J. Mbanga and C. Dube
  A study was carried out to determine endo and ecto-parasites in Matebeleland North and South from free range chickens (Gallus domesticus). Only adult chickens were selected for determination of parasite. For intestinal parasites microscopic studies of eggs and faecal egg counts were done using the salt floatation technique. The endo parasites encountered in the study were Tetrameres americana, Acuaria hamulosa, Ascaridia galli, Heterakis gallinarum, H. dispar, Allodapa suctoria, Capillaria annulate, Raillietina echinobothrida and R. tetragona. A commercially prepared insecticide constituted as follows (0.02% Tetamethrin, 0.03% pramethrin and 0.034% Imiprothrin) was applied for 2 seconds and feathers were then gentle unruffled so that ectoparasites could be counted and identified. Ecto parasites recorded in this study were Menopon gallinae, Menacanthus stramineus, Dermanyssus gallinae, Argas persicus, Ornithonyssus bursa, Cnemidocoptes mutans, Echidnophaga gallinacean, Gonocoites gallinae and Gonocoites hologester. The birds under study showed slow growth, poor egg hatching. Parasites should have contributed substantially to this poor growth although not single handedly.
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