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Articles by S. Dede
Total Records ( 2 ) for S. Dede
  E. Ceylan , S. Dede , Y. Deger and I. Yoruk
  The aim of the study was to investigate the effect of carrying heavy load for a long time on lipid peroxidation (MDA: malondialdehyde), NO2 (nitrite), NO3 (nitrate), antioxidants (GSH: reduced glutathione, retinol, α-tocopherol) and vitamin D3 in healthy horses. Blood samples from seventeen native 3-5 years age and 450-500 kg live weight Anatolian horses carried a load which comprised at least 30% of their body weight and for 4 h on mountainous terrain (hard working) were evaluated. Blood samples were collected in the morning before the animals started to carrying load and immediately after they finished carrying (working). It is observed that the level of MDA, NO2 and NO3 increased significantly (p<0.05) after working. While GSH concentration, increased after working; levels of retinol, α-tocopherol and vitamin D3 levels decreased significantly (p<0.05). On the other hand, the vitamin D3 levels were affected by hard working as other lipid soluble vitamins. There were a correlation between the physiological response to hard-working and some oxidant markers in healthy-hard working horses. These observations provide evidence that hard-working increases oxygen consumption and cause a disturbance of intracellular pro-oxidant-antioxidant homeostasis.
  D. Kilicalp , S. Dede , Y. Deger and L. Aslan
  It was reported that the effects of green tea on the mineral levels of testis and liver of Guinea pigs exposed to a 900 MHz electromagnetic field. Four experimental groups labeled as controls (Group A), irradiated (Group B), irradiated receiving green tea extract (Group C) and green tea only (Group D) were formed with seven randomly chosen animals of both sexes in each group. After exposure for one month, the animals were sacrificed by decapitation and testis and liver samples were collected for biochemical analysis. In female Guinea pigs irradiation with and without green tea as well as green tea alone caused significant changes of the iron levels in liver, but no significant changes of manganese, copper, zinc and the copper/zinc ratio. In males, irradiation caused significant increases of manganese and a decrease of the iron levels in liver and of manganese, copper, zinc in testis. Combined with green tea, electromagnetic radiation resulted in changes of manganese, iron, copper and copper/zinc ratio in liver and of manganese only in testis. Green tea alone changed the levels of hepatic iron, zinc and copper/zinc ratio and of testicular concentrations of iron and zinc. The highest levels of copper were found in the liver tissue of the irradiated animals that were also treated with green tea. From present findings we can state that testis tissue is more sensitive to electromagnetic radiation than liver tissue, showing greater changes in trace mineral metabolism. Green tea brings the trace element levels to near normal values; supporting the idea that green tea as a supplement has a protective effect against the damaging effects of electromagnetic radiation.
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