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Articles by S. Chanaphat
Total Records ( 2 ) for S. Chanaphat
  T. Taechowisan , N. Chuaychot , S. Chanaphat , A. Wanbanjob and P. Tantiwachwutikul
  In an attempt to understand the mode of action of this antagonist in nature, the interaction between Streptomyces sp. SRM1 and C. musae was studied by dual culture on agar plates. Evidence for the antibiosis of Streptomyces sp. SRM1 was demonstrated by inhibition zones in in vitro plate assay. The crude extract from the culture of Streptomyces sp. SRM1 also produced antifungal activity, which showed antagonistic effects against C. musae such as swelling, distortion and excessive branching of hyphae and inhibition of spore germination. An indirect method was used to show antagonistic effect of Streptomyces sp. SRM1 against C. musae in soil. This study suggests the potential of developing Streptomyces sp. SRM1 for the biological control of anthracnose disease of banana caused by C. musae.
  T. Taechowisan , N. Chuaychot , S. Chanaphat , A. Wanbanjob and Y. Shen
  Four flavonoids including kaempferol (1), isoscutellarin (2), umbelliferone (3) and cichoriin (4) have been isolated from Streptomyces sp. Tc052, an endophyte in the root tissue of Alpinia galanga Swartz. The evaluation for protective effect of compounds 1-4 against glutamate-induced cytotoxicity in hippocampal HT22 cell line was conducted. Compounds 1 and 2 showed significant effective protection ratios of 62.4+2.8 and 55.3+3.4%, respectively, at a concentration of 100 μM, whereas compounds 3-4 were inactive. Compounds 1 and 2 showed potent scavenging effects on DPPH radical exhibiting IC50 value of 60.74 and 75.65 μM, respectively. These results suggest that compounds 1 and 2 may possess the neuroprotective activity against oxidative cellular injuries.
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