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Articles by S. Amin
Total Records ( 6 ) for S. Amin
  P. Kumar , A. Semalty , S.R. Mir , M. Ali and S. Amin
  The plant Pongamia pinnata (Linn.) Pierre of family Leguminosae sub-family Papilioanaceae was evaluated for its hypoglycemic and hypolipidemic activity in streptozotocin induced diabetic rats. A new difuranoflavonone Compound PP (named Pongamiaflavonol), isolated from methanlolic extract of P. pinnata pods by column chromatography, was also studied for the activity. It was observed that after 14 days of treatment blood glucose level was reduced by 66.34, 54.82, 63.62 and 67.48 % with Std. Glibenclamiade 3 mg kg-1), P. pinnata pods (300 mg kg-1), P. pinnata flowers (300 mg kg-1) and PP (100 mg kg-1), respectively. The lipid profile was also studied and was found to be normalized significantly by both the flowers and pods extracts of P. pinnata and compound PP.
  A. Semalty , M. Semalty , P. Kumar , S.R. Mir , M. Ali and S. Amin
  Pongamia pinnata (family Papilionaceae) has been used for bronchitis, whooping cough, rheumatic joints and quench dipsia in diabetes. This study deals with the isolation of a new hypoglycemic phytoconstituent from P. pinnata pods. The hypoglycemic activity of the isolated phytoconstituent was evaluated in comparison of the methanolic extract of the pods.. Methanolic extract of P. pinnata pods was fractionated by column chromatography and the isolated compounds were identified by spectral analysis. A new compound named Pongamiaflavonylflavonol was isolated from chloroform: methanol (97:3) eluant. This new isolated compound was studied for hypoglycemic activity in streptozotocin induced diabetic rats. Methanolic extract of P. pinnata pods and pongamiaflavonylflavonol showed significant hypoglycemic activity in streptozotocin-induced hyperglycemic rats after oral administration. At the end of 6 h the new compound showed 12.15% reduction in blood glucose level in comparison of extract (11.36%) against the standard (16.93%). It can be concluded that the novel Pongamiaflavonylflavonol isolated from P. pinnata pods may be useful as oral hypoglycemic therapeutic agent. This may serve as a lead compound for development of more potent drugs for clinical use in diabetes.
  S. Nasseri , M. Dehghani , S. Amin , K. Naddafi and Z. Zamanian
  Atrazine, a herbicide widely used in corn production, is frequently detected as pesticide in water resources. In this research, four agricultural fields with a long history of atrazine application in Shiraz and its vicinity in Fars province of Iran, have been studied to determine the fate of atrazine through the passage of time. These four farms were cultivated under a crop rotation (corn-wheat) during the past 10 years. Samples were collected from four soil profiles of 0-10, 10-20, 20-40, and 40-60 cm soil depth at different times. The time intervals for soil sampling started before atrazine application and continued until no atrazine was detected. According to the general linear model, there was no significant difference between atrazine residual concentrations and the soil moisture and depth (p≥0.05). But, significant difference between atrazine residual concentrations and the sampling regions was observed (p<0.001). Based on the data, atrazine leaching and dissipation rate in different soil profiles in the four sampling regions were high and significant. Therefore, there is a high risk of atrazine pollution in groundwater resources of the region.
  M Dehghani , S. Nasseri , S. Amin , K. Naddafee , M. Taghavi , M. Yunesian and N. Maleky
  In this study several agricultural fields with a long history of atrazine application in Fars province of Iran have been explored for their potential of atrazine biodegradation. After several subculturing for a period of 300 days acclimation, leads to an enhancement of atrazine biodegradation rate. A successful enrichment culture with a high capability for atrazine degradation was obtained (88%). A combination of enrichment culture technique, in a basal salt medium containing atrazine and carbon sources under nitrogen limitation and plating on indicator atrazine agar, have permitted the isolation of bacterial consortium with high capability of using atrazine as a nitrogen source. Seven gram-negative and one gram-positive bacterial strain, which were able to use this herbicide as a sole source of nitrogen, were isolated from Darehasalouie Kavar corn field soil. Based on physiological, biochemical and nutritional characteristics, the isolated bacteria were identified as Pseudomonas alcaligenes, Acidovorax sp., Pseudomonas putida, Ralstonia eutrophus, Pseudomonas syiringe, Erwinia tracheiphila, Entrobacter agglomerans and Micrococcus varians. Therefore, the bacterial consortium in liquid culture containing carbon sources and atrazine as a sole source of nitrogen, degrade added atrazine more than 80%.
  I. Nazish , R.A. Kaskoos , S.R. Mir , S. Amin and M. Ali
  Ruta graveolens L. belonging to family Rutaceae is commonly known as Common rue and locally as Sudab in India. It is an important medicinal plant used in capillary fragility, for eye diseases, as stimulant and emmenagogue. As the herb is used widely in the Indian traditional system, it was thought worthwhile to undertake the standardization of its aerial parts. Aerial parts consist mainly of leaves that are 3-5 inch long, flowers are tetramerous and fruits are 4-5 lobed. In the powdered form it had pungent odor and exceedingly bitter taste. Microscopical examination of powder of aerial parts showed fragments of epidermis, glandular trichomes, stone cells, lignified xylem elements and abundant calcium oxalate crystals. Successive extractive value was highest in aqueous extract (16.08% on dry weight basis). Mean ash values (%) were 8.13 (total), 2.01 (acid insoluble ash) and 1.02 (water soluble ash). Loss on drying was found to be 4.03% and pH values of aqueous extract was 6.74. Bitterness value of aerial parts was 1.28; foaming index was less than 100. Screening of all extracts indicated the presence of all phytoconstituents except saponins. TLC fingerprints of extracts of aerial parts were also developed.
  R.A. Kaskoos , S. Amin , M. Ali and S.R. Mir
  The present study was aimed to describe the fatty acid composition, stability and nutritional characteristics of fixed oil of Olea europaea drupes from Iraq, locally known as Zaytoon. The oil is commonly known as olive oil and is used throughout the world and is believed to have an important role in human health and nutrition. It is considered as one among newer source of edible oil. The oil is classified as generally regarded as safe (GRAS). The fact that there are few reports of analysis of olive oil from Iraq in comparison to other parts of the world also lured us to examine chemically. Fatty acid composition of the olive oil was determined by capillary GC-FID. Thirty fatty acids (95.88%) were identified in the oil. The major fatty acids of the oil were oleic acid (68.07±1.089%), palmitic acid (12.12±0.162%), arachidic acid (9.78±0.155%), docosahexaenoic acid DHA (2.65±0.041%) and eicosapentaenoic acid EPA (0.53±0.01). The DHA and EPA are highly valued polyunsaturated fatty acid (PUFA) and part of several health foods and nutraceuticals. Peroxidizability index calculated for the oil was 27.37% and unsaturated/saturated ratio was 3.25. High unsaturated fatty acid content signified its potential as a health promoter. Moreover, it can be expected to offer considerable resistance to oxidative rancidity during storage.
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