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Articles by S. Moin
Total Records ( 2 ) for S. Moin
  M.R. Sulaiman , S. Moin , A. Alias and Z.A. Zakaria
  The present study was carried out to determine the antinociceptive and anti-inflammatory activities of the ethanolic extract of Sida rhombifolia L. leaves in various animal models. The antinociceptive activity was measured using the abdominal constriction test and hot plate test, while the anti-inflammatory was assessed using the carrageenan-induced paw edema test. The dried leaves of S. rhombifolia was mixed with 95% ethanol (1: 10; w/v), incubated in water bath (55°C) for 72 h, filtered and evaporated to dryness (50°C) under reduced pressure. The sticky paste of extract was then emulsified using 0.1% Tween-80 in normal saline at concentrations required to produce doses of 30, 100 and 300 mg kg 1 body weight. Based on the data obtained, all doses of the extract, administered intraperitoneally, exhibited significant (p<0.05) antinociceptive and anti-inflammatory activities in a dose-dependent manner. In conclusion, the leaves of S.rhombifolia possessed antinociceptive and anti-inflammatory activities and confirms its traditional uses in the treatment of pain-and inflammatory-related ailments.
  M.R. Sulaiman , Z.A. Zakaria , S. Moin , M.N. Somchit and Y.S. Chai
  The present study was carried out to establish the antinociceptive and anti-inflammatory activities of the aqueous extract of Lonicera japonica flowers’ buds in various experimental animal models. The antinociceptive activity was measured using the abdominal constriction, hot plate and formalin tests, while, the anti-inflammatory was measured using the carrageenan-induced paw edema. The dried flower’s buds of L. japonica was added with distilled water (1:10 w v 1) and boiled for 2 h at 80°C. The supernatant collected was freeze-dried overnight and prior to use was diluted to the desired doses. The extract (30, 100 and 300 mg kg-1; administered intraperitoneally) exhibited significant (p<0.05) antinociceptive and anti-inflammatory activities in all assays used. In conclusion, the flower’s buds of L. japonica possessed potential antinociceptive and anti-inflammatory activities that require further in-depth studies.
 
 
 
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