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Articles by S. J. Wilson
Total Records ( 2 ) for S. J. Wilson
  A. Foo J. Y. and S. J. Wilson
  Studies have demonstrated that a notable increase in arterial stiffening can signify the presence of cardiovascular abnormalities, such as hypertension. Presently, the mercury sphygmomanometer continues to be the clinical gold standard to identify such abnormalities, but due to its measuring nature it cannot be used for continuous observation. Pulse transit time (PTT), which has an inverse relationship with blood pressure (BP), is proposed here as a simple and non-invasive technique to monitor hypertension in children. In order to minimize inter-subject PTT differences, all obtained PTT data were normalized to the study population. The results indicated that normalized mean PTT value is able to differentiate hypertensive from normal children in a significant (p < 0.01) manner in both upper and lower limbs. Preliminary findings herein suggest that PTT can be useful tool to monitor for hypertension in children especially during prolonged clinical observations.
  J. Y. A. Foo and S. J. Wilson
  A simple and non-invasive technique, termed pulse transit time (PTT), has shown its potential in long-term investigations such as respiratory sleep studies and cardiovascular studies. Based on these findings, the PTT technique shows relevance for continuous haemodynamic monitoring in critical care. The objective of this review is to understand the potential, applications and limitations of PTT in this clinical setting. Present non-invasive haemodynamic monitoring methods such as automated oscillometric blood pressure (BP) and auscultatory techniques have their known limitations. They tend to underestimate systolic BP while overestimating diastolic BP. Due to the periodic increase in cuff pressure cycles during data acquisition, these techniques may cause much discomfort in elderly geriatric patients, or lessen the cooperation of younger paediatric patients. Thus, there can be adverse effects on therapeutic decisions and possibly clinical outcomes. Documented evidences have indicated that changes observed in PTT are inversely correlated to the corresponding BP changes. In critical care, a simple and accommodating technique like PTT may be useful in providing better comfort for patients during extended monitoring. Being a semi-quantitative measure, blanket recommendations for its utility can then become possible. The basic instrumentations needed are often part of standard critical care monitoring system. Furthermore, PTT also has the potential to monitor the often tachypnoeic respiratory dependent BP changes seen in small infants during critical care.
 
 
 
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