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Articles by S. Ignacimuthu
Total Records ( 2 ) for S. Ignacimuthu
  P. Subash-Babu and S. Ignacimuthu
  Hyponidd, a herbomineral formulation composed of 10 medicinal plants extracts. We have investigated the hyponidd on prevention of oxidative stress and antihyperlipidemic effect in streptozotocin (STZ) induced diabetic rat brain. Rats were rendered diabetic by STZ (45 mg kg-1 body weight). After induction of diabetes rats were treated with hyponidd (100 and 200 mg kg-1) for 45 days. After 45 days treatment, significant reduction in fasting blood glucose, thiobarbituric acid reactive substances, hydroperoxides and lipid profiles (Cholesterol, Triglycerides and Free fatty acids). Hyponidd also caused a significant (p<0.05) increase in reduced glutathione, superoxide dismutase, catalase and glutathione peroxidase in the brain of STZ-induced diabetic rat, suggesting its role in protection against lipid peroxidation induced membrane damage. The results clearly showed that the hyponidd effectively restores antioxidant status and lipid profiles in the brain of STZ-diabetic rat.
  M. Ayyanar and S. Ignacimuthu
  Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. Therapeutically interesting and important drugs can be developed from plant sources which are used in traditional systems of medicines. Indian traditional system of medicine is based on empirical knowledge of the observations and the experience over millennia and more than 5000 plants are used by different ethnic communities in India. The present communication constitutes a review on the medicinal properties and pharmacological actions of Cassia auriculata L. and Cissus quadrangularis Wall. used in Indian traditional medicine. These plants are known to contain various active principles of therapeutic value and to possess biological activity against a number of diseases.
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