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Articles by Rula Khuzaie
Total Records ( 2 ) for Rula Khuzaie
  Mahmoud Abu -Samak , Rula Khuzaie , Mohammad Abu-Hasheesh , Malak Jaradeh and Mohammad Fawzi
  The purpose of this research was to investigate the association between weights status, as measured by Body Mass Index (BMI) and vitamin B12 levels among male Jordanian youth. Recent studies have shown correlation between Body Mass Index (BMI) and serum vitamin B12 levels in some Middle East countries; however, no data are available for Jordan, where the prevalence of vitamin B12 deficiency has increased at an alarming rate. One hundred and twenty male university students (aged 18 to 24 years) from Amman city, Capital of Jordan, were divided into three groups according to the body mass index namely healthy weight, overweight and obese. Fasting samples were collected for hematological parameters, serum leptin, vitamin B12, folic acid and blood glucose. The mean serum vitamin B12 level was decreased in overweight students (283 . 2 ± 84 . 17) pg mL1 comparing with the mean of all groups (353.73 ± 125) pg mL1. Of all students 16 % had B12 deficiency ( < 200 pg mL1) and 65 % of them were overweight. Serum folate levels were normal in all groups. BMI was positively correlated with serum leptin levels in all groups. Significant elevation was observed of white blood cells count in obese group (p < 0.001). Present findings suggest that overweight youth are a risk group for vitamin B12 deficiency.
  Mahmoud Abu-Samak , Al-Motassem Yousef , Ahmad Al-Jarie , Hisham Y. Al-Matubsi , Ahmed Abu-zaiton, , Mamoun Al-Quraan and Rula Khuzaie
  To analyze the influence of hyperleptinemia on fasting lipid and hematological parameters in healthy Arab male youth in Jordan, this cross-sectional study was carried out in April 2009 on a sample of 120 students aged 18-24 years. Subjects were stratified by fasting leptin into two groups (control, <12.7 ng mL-1 vs. hyperleptenimic, e_<12.7 ng mL-1) and BMI (normal weight, <25 kg m-2 vs. overweight/obese, BMI e_<25 kg m-2). Fasting serum leptin, blood glucose, lipid profile and hematological parameters values were determined by standard kit methods. Mean serum leptin concentrations were more than five times as high in hyperleptenemic subjects than in control subjects (p<0.001). Compared with control group, significant elevations (p<0.01) were observed in the means total cholesterol, LDL cholesterol and triglyceride levels of hyperleptenemic group whereas no significant differences was detected in HDL-cholesterol. Except the changes of WBC count, MCH and slightly MCHC, there were no differences between both groups in any other term of hematological parameters. In conclusion, changes in lipid variables and some hematological parameters may increase plasma viscosity as a step during atherosclerosis pathogenesis in male youth at risk for dyslipidemia and cardiovascular diseases. Thus, hyperleptinemia could be a useful index in identifying healthy youth male subjects but this hypothesis needs further investigation.
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