Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
 
Articles by Rehab Omer
Total Records ( 2 ) for Rehab Omer
  Rehab Omer , Afaf I. Abuelgasim and B. Elmahdi
  Twenty four Wistar albino rats were divided into 4 groups and treated orally with potassium bromate at doses of 0, 50, 100 and 200 mg kg-1 body weight (b.wt.) for 21 days. Rats received 200 mg kg-1 b.wt. died within 18 days. A significant reduction in Hb, PCV and MCHC values were observed in animals received 200 mg kg-1 b.wt. in the second week while no changes occurred in the groups treated with 50 and 100 mg kg-1 b.wt. The activity of alanine transaminase (ALT) was significantly increased in rats received 100 and 200 mg kg-1 b.wt. of potassium bromate from the first week, while total protein and albumin were significantly decreased from the first week in animals treated with 200 mg kg-1 b.wt. and the second week at the dose 100 mg kg-1 b.wt. Histologically liver degeneration and haemorrhage was evident in the groups treated with 100 and 200 mg kg-1 b.wt. The dose of 50 mg kg-1 b.wt. did not cause any changes compared to the control.
  Afaf I. Abuelgasim , Rehab Omer and B. Elmahdi
  The present study aimed to clarify the toxic effect of potassium bromate in Wistar albino rats. Thirty rats were divided into 5 groups. The first group severed as control and the other four groups received potassium bromate orally at doses 50, 100, 200 and 400 mg kg-1 body weight (b.wt.) for 21 days. Rats received 400 mg kg-1 b.wt. died within 3 days and those received 200 mg kg-1 b.wt. died on the 18th day post treatment. The body weights of rats treated with potassium bromate were not affected but the relative weights of the kidney and liver were significantly increased (p<0.05) in the group of rats received 100 mg kg-1 b.wt. potassium bromate compared to the control group. Clinically difficulty in breathing and depression occurred in those rats received 100 and 200 mg kg-1 b.wt. of potassium bromate. A significant (p<0.05) increase of urea, creatinine and potassium beside a decrease in Na level was evident in the groups received 100 and 200 mg kg-1 b.wt. of potassium bromate. Histopathological examination of the groups of rats received 100, 200 and 400 mg kg-1 b.wt. showed generalized congestion, haemorrhage and degenerative changes in the kidney and liver. Also increased intestinal goblet cells, stomach epithelium desquamation, pneumonia, haemorrhage, neuronal degeneration and vaculation of the brain were evident. The group of rats received 50 mg kg-1 b.wt. of potassium bromate was not affected compared to the control.
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility