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Articles by Rashid Ali
Total Records ( 2 ) for Rashid Ali
  Zafar Rasheed , Rizwan Ahmad , Naila Rasheed , Trivendra Tripathi and Rashid Ali
  The study hypothesized that oxidative by-product like hydrogen peroxide (H2O2), would reacts with hemoglobin (Hb) and help to initiate autoimmunity in patients with type 1 diabetes. To test this hypothesis, Hb was modified by reactive oxygen species (ROS). Modification incurred in Hb was characterized by physico-chemical techniques. ROS-modified Hb was found to be highly immunogenic in rabbits as compare to native Hb. The binding characteristics of circulating autoantibodies in type 1 diabetes patients against native and ROS-modified Hb were assessed. Diabetes patients (n = 39) were examined by direct binding ELISA and their results were compared with healthy age-matched controls (n = 22). High degree of specific binding by 48% of patient`s sera towards ROS-modified Hb, in comparison to its native analogue (p<0.05) was observed. Competitive inhibition ELISA reiterates the direct binding results. Collectively, ROS caused extensive damage to Hb altering its immunogenicity, the neo-epitopes, thus generated might play a role in the induction of circulating autoantibodies in type 1 diabetes mellitus.
  Omran Al-Shamma , Rashid Ali and Haitham S. Hasan
  All aircraft, military and commercial, must satisfy controllability and in turn, maneuverability prerequisites to be espoused by the military or certified for transport aircraft. So, it is imperative for the designers to assess the control authority of candidate configurations early in the preliminary design phase. This early assessment formulates the design process very proficient and cost-effective. Aileron sizing is one of the controllability concepts that should be involved in the preliminary design process. Adding aileron sizing module as a helpful tool for aeronautical students enhance their knowledge, understanding and analyzing studies. This study presents a programmable algorithm for aileron sizing to be employed in any preliminary aircraft design software. The study introduced the necessary formulae as a guide to size the aileron to achieve the prerequisites of the roll control. A solved example has been added to explain the application of the algorithm.
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