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Articles by R.G. Belemtougri
Total Records ( 2 ) for R.G. Belemtougri
  R.G. Belemtougri , S.A. Dzamitika , Y. Ouedraogo and L. Sawadogo
  The present study was done to evaluate the hypotensive properties and the mechanisms action of the leaf aqueous extract in anaesthetized normotensive rats through a direct blood pressure measurement. The results showed that the extract caused a dose dependent fall in mean arterial pressure. Bilateral vagotomy did not abolished the hypotension induced by S. birrea. Pretreatment of rats with atropine, piperoxan and practolol did not abolished hypotension and suggests that muscarinic, α2 and β2 receptors are not involved in the induction of hypotension. These results suggest that the hypotensive effect of the extract is likely to be mediated through other factors like nitric oxide release or intracellular calcium decrease.
  B. Bayala , P.B. Telefo , I.H.N. Bassole , H.H. Tamboura , R.G. Belemtougri , L. Sawadogo , B. Malpaux and J.L. Dacheux
  Testis histology and sperm parameters were used to evaluate the antispermatogenic effect of Leptadenia hastata aqueous extract in male Wistar rats. 100, 200, 400 and 800 mg kg-1 of Leptadenia hastata aqueous extracts were orally administered during 60 consecutive days. L. hastata aqueous extract did not have significant (p>0.05) effect on body, testis and epididymis weights. Testes histology of rats treated with the plant extract showed the decrease of Leydig cells number and the spermatogenesis was been influenced with high doses of L. hastata aqueous extracts. Some sperm parameters as path velocity, progressive velocity, straightness, linearity and motility of spermatozoa were been significantly (p<0.05) decreased. The treated rats with the different amount of L. hastata aqueous extracts showed a significant (p<0.01) reduction in the number of sperm in the testis and the cauda epididymis. Even if its not significant, the extract showed a decrease of testes, epididymis weights and a rarity of Leydig cells. These results confirm the antiandrogenic effect of L. hastata and the claims of breeders that the consumption of the leaves of L. Hastata reduced the fertility of their animals.
 
 
 
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