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Articles by R. Suraj
Total Records ( 3 ) for R. Suraj
  J. Anbu Jeba Sunilson , R. Suraj , G. Rejitha , K. Anandarajagopal , A.V. Anita Gnana Kumari and P. Promwichit
  In the present study, antimicrobial activity of various extracts of Zingiber officinale, Curcuma longa and Alpinia galanga were screened against the common food borne bacteria such as Escherichia coli, Salmonella enteriditis, Clostridium perfringens, Staphylococcus aureus, Campylobacter jejuni, Bacillus cereus and fungi such as Saccharomyces cerevisiae, Hansenula anomala, Mucor mucedo, Candida albicans using disc diffusion method. All the extracts showed significant antibacterial and antifungal properties. The methanol extracts (100 μg mL-1) revealed maximum zone of inhibition (p<0.001). Zingiber officinale and Curcuma longa possessed considerably greater activity than Alpinia galanga. These findings established the potential of the selected rhizomes of Zingiberaceae family as effective natural food preservatives.
  J. Anbu Jeba Sunilson , R. Suraj , K. Anandarajagopal , G. Rejitha , M. Vignesh and P. Promwichit
  In this study, petroleum ether, chloroform and methanol extracts of Codium decorticatum showed the presence of amino acids, carbohydrates, saponins, phytosterols, alkaloids and glycosides. The antibacterial activity against Gram-positive bacteria, such as Streptococcus pneumoniae, Staphylococcus aureus and Gram-negative bacteria, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Pseudomonas aeruginosa was carried out using cup-plate method. All the extracts showed good zone of inhibition against S. pneumoniae and K. pneumoniae at the concentrations of 25, 50 and 100 mg mL-1 compared with standard drugs, gentamicin and ampicillin (30 μg mL-1). To standardize the algae, elemental analysis was also carried out on C. decorticatum powder which revealed the presence of various elements. The present findings show the importance of C. decorticatum in producing new compounds having antibacterial activity.
  J. Anbu Jeba Sunilson , M. Muthappan , Amitava Das , R. Suraj , R. Varatharajan and P. Promwichit
  Coccinia grandis Linn. (Cucurbitaceae) is a perennial branched handsome tendril climber, distributed through out India. It has been used in folk medicine for the treatment of jaundice. The aim of this work was to study the hepatoprotective effect of crude ethanolic and aqueous extracts from the leaves of C. grandis against liver damage induced by CCl4 in rats. The ethanolic extract at an oral dose of 200 mg kg -1 exhibited a significant (p<0.05) protective effect as shown by lowering serum levels of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase, total bilirubin and total cholesterol and increasing levels of total protein and albumin levels as compared to silymarin, the positive control. These biochemical observations were supported by histopathological examination of liver sections. The activity may be due to the presence of flavonoid compounds. The extracts showed no signs of acute toxicity up to a dose level of 2000 mg kg -1. Thus it could be concluded that ethanolic extract of C. grandis leaves possesses significant hepatoprotective activity.
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