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Articles by R. Rajabian
Total Records ( 2 ) for R. Rajabian
  K. Moradzadeh , B. Larijani , A.A. Keshtkar , A. Hossein-Nezhad , R. Rajabian , I. Nabipour , G.H. Omrani , A. Bahrami , M.M. Gooya and A. Delavari
  There is no agreement about normal level of vitamin D and its deficiency stages. For finding normative value of Vitamin D and evaluating the state of vitamin D level in Iranian population we revised the data that was collected in Iranian national Multi-center Osteoporosis Study (IMOS). We chose 5 cities with different climates; individuals were selected by random cluster sampling. Healthy people aged 20-69 were entered into the study and serum vitamin D and PTH levels were measured. We stratified subjects based on their vitamin D levels in 7 groups and compared mean PTH levels of adjacent groups. We evaluated 5329 blood samples for vitamin D and PTH and found three steps of PTH elevation with decreasing vitamin D levels for women (40, 25 and 12 nmol L-1) and two (35 and 25 nmol L-1) for men. We use these values as cutoff levels for definition of normal, mild, moderate and severe vitamin D deficiency states. Based on these cutoffs, prevalence of all stages of vitamin D deficiency was unexpectedly high in all cities. Vitamin D deficiency state was seen in 75.1% of women and 72.1% of men. The high prevalence of vitamin D deficiency in Iran is similar to the results of other studies in Middle East area and indicates a need for a careful search for a determination of cause and need for regular fortification program.
  S.E. Ghiasi , R. Valizadeh , R. Rajabian , R. Jalal and B. Azimian
  The aim of this study was to evaluate the effect of chromium-methionin supplementation in high dosage on blood parameters and Insulin Resistance (IR) index in fructose induced insulin resistant rats. At first stage of the experiment, ten wistar rats were assigned as the healthy control group and sixteen rats were given Fructose (Fr) for 5 weeks in order to inducing insulin resistance. In the 2nd stage the insulin resistant rats were divided into Cr-fed group that additionally fed 1000 μg day-1 chromium as Chromium-L-Mmethionin (Cr-Met) and insulin resistant rats with no chromium supplementation for 6 weeks. In the first stage, IR was significantly induced (p<0.05) in rats receiving Fr. Plasma Fasting glucose, insulin, IR index and triglyceride contents were significantly (p<0.05) increased in Fr-fed group in comparison with the control. According to the results of second stage, IR index significantly (p<0.05) decreased after Cr-Met supplementation. The fasting insulin, glucose and triglycerides concentrations in Cr-Met treated group were lower (p<0.05) than the Fr-fed insulin resistant group. The results of this study indicated that chromium supplementation as Cr-Met could be effective for lowering IR index, fasting insulin, glucose and triglyceride in insulin resistant rats.
 
 
 
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