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Articles by R. Mowla
Total Records ( 2 ) for R. Mowla
  S.K. Biswas , A. Chowdhury , S.Z. Raihan , M.A. Muhit , M.A. Akbar and R. Mowla
  Kalanchoe pinnata is used in traditional medicines for the treatment of several health problems in Bangladesh. The study was designed to investigate the cytotoxicity and antibacterial activities of the chloroform extract of the leaves of Kalanchoe pinnata. Qualitative phytochemical analysis was also performed for the identification of several phytochemical compounds such as alkaloids, glycosides, steroids, gums, flavonoids, saponins, reducing sugar, tannins and terpenoids. The study revealed that the plant extract contained all of the phytoconstituents except steroids, flavonoids and terpenoids. The agar disc diffusion technique was used to investigate the antibacterial activities of the plant extract at 500 μg disc-1 against eight bacterial strains. The plant extract showed very low antibacterial activities with zone of inhibition ranging from 0.33±0.02 to 1.67±0.02 mm, while the maximum antibacterial action was recorded against E. coli with zone of inhibition of 1.67±0.02 mm but no sensitivity was found against V. cholerae. The antibacterial activity of the plant extract was compared with the standard drug, Levofloxacin which was used at 10 μg disc-1. Brine shrimp lethality bioassay was also done to find out the cytotoxic activity of the plant sample. The chloroform extract of the plant showed lethality against the brine shrimp nauplii (LC50: 125.89 and LC90: 234.42 μg mL-1. Finally, it was concluded that the chloroform extract of the plant leaves possessed considerable cytotoxic activity with less antibacterial potentials.
  U.K. Karmakar , S.K. Biswas , A. Chowdhury , S.Z. Raihan , M.A. Akbar , M.A. Muhit and R. Mowla
  The ethanol extract of Asparagus racemosus Willd was examined for antbacterial and antioxidant properties. Phytochemical investigation was also done to identify the presence of phytochemical compounds. The ethanol extract at the concentration of 500 μg disc-1 showed moderate antibacterial activity against Staphylococcus saprophyticus, Enterococcus faecalies, Streptococcus agalactiae and Escherichia coli with zone of inhibition of 7.77±0.37, 6.07±0.06, 10.10±0.11 and 6.00±0.04 mm, respectively while 250 μg disc-1 of the extract did not reveal any zone of inhibition against the tested bacterial strains. Antioxidant activity of the ethanol extract was determined according to their scavenging activity of the stable DPPH (1,1-diphenyl-2-picryl hydrazyl) free radical and 10% H2SO4. In the qualitative antioxidant assay, the extract showed free radical scavenging properties. Preliminary phytochemical analysis of the plant extract showed the presence of alkaloids, tannins, saponins, glycosides, flavonoids and carbohydrates which could be responsible for antibacterial and antioxidant properties justifying the ethnomedicinal applications of Asparagus racemosus. Thus, further advanced research is necessary to isolate and characterize the chemical compounds responsible for the therapeutic activities of the plant.
 
 
 
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