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Articles by R. Ghorbani
Total Records ( 3 ) for R. Ghorbani
  G.R. Irajian , M. Nassaji , R. Ranjbar , A. Beheshti , R. Ghorbani , S. Salmanzadeh-Ahrabi , S. Ramazanzadeh , E. Moshiri , A. Karami , M.J. Hosseini , N. Bazzaz , N. Jonaidi Jafari and M. Izadi
  In this study, directly observed short course therapy (DOTS) was implemented to control tuberculosis in a camp in Iran. First, one study had been conducted in 1996 (before DOTS implementation) as active case finding then DOTS have been implemented in 1997. Another study was carried out in 2004 for evaluation of the effects of DOTS. In the first study, 16 patients with pulmonary TB (50% smear positive) were detected. During the years of DOTS implementation, the number of TB cases decreased significantly. In the second study, no pulmonary TB was detected. Our experience showed that DOTS significantly and effectively decreases TB in refugees and leads to a high cure rate and prevents death.
  M. Faranoush , G.R. Bahoush A. Mehrvar , S. Hejazi , P. Vossough , A.A. Hedayatiasl , M.S. Rahiminejad , F. Seighali , R. Ghorbani and M.A. Ehsani
  Wilms tumor is the most common childhood renal tumor accounting for about 6% of pediatric malignant disease. Most patients with Wilms tumor can be cured with treatment and subsequently lead normal life. The multidisciplinary management of Wilms tumor has resulted striking improvement in survival of more than 85% nowadays and has become a paradigm for successful cancer therapy. We describe the results of patients treated according to National Wilms Tumor studies (NWTS) 3-5, with surgical staging, Central pathology review and multimodality treatment. This is a historical cohort study on the all patients who had Wilms tumor. We used the existing files of all patients who had admitted to Ali Asghar Children’s hospital with Wilms tumor in the years of 1990-2003. The patients evaluated for age, sex, histologic type of cancer, metastasis, outlook of relapse and outcome after 5 years from diagnosis. We analyzed 175 files of Wilms tumor. They are 49.7% are male and 50.3% female. Mean age (±S.D.) of patients at diagnosis was 3.8±0.4 year. The 5-year survival rate of these patients was approximately 76±4%. History of cancer in first degree of relative was 11.5% and family marriage was 36.4%. Tumor involvement were 45.3% in right kidney, 51.5% in left kidney and both kidney involvement in 3.2%. Congenital anomalies in association with Wilms tumor were urologic problem (1.5%), hemihypertrophy (0.5%), sporadic aniridia (0.5%) and without abnormalities (97.5%). Histologic type of tumor were 32.6% favorable, 65.2% unfavorable and 2.2% intermediate. Stage II and III were the most common (35.4 and 32.4%, respectively). Tumor relapse were occurred in 25.4%.
  A. Azarkeivan , A. Mehrvar , M. Faranoush , P. Vosough , N. Mehrvar , R. Ghorbani , A. Shahmohamadi , M.A. Ehsani and A.A. Hedayatiasl
  Thalassemia is accounted as the most common hereditary anemia through our region. Appropriate therapy for this disease includes a regular monthly blood injection. However, in the approach patients will inevitably confront with side effects particularly iron overloads in critical organs including heart, ductless glands and liver. In this study, we wanted to consider the heart abnormalities in patients with β thalassemia, who received blood transfusion. In this study, 139 patients with β thalassemia (major and intermedia) enrolled, who referring to medical centers linked with the Iranian blood transition institute and Ali Asghar hospital. History about blood transfusion, iron chelation were taken. Physical examination were done too. Heart abnormalities have considered by echocardiography method. The mean (±SD) age was 21.1±7.1 years. Mean duration of treatment was 22.6±13.7 years. The 95.5% of patients had not respiratory problems. Mean (±SD) of ferritin was 1536.2±1609.6 ng dL-1. The 26.5% had cardiac problems. In these patients, 4.3% had previous asthma, 12% complained from palpitation, 10% used drugs for their heart problems and at last 5.8% had cardiomegaly. In order to our results and previous researches we can say that heart can be considered as a primary site for iron deposition and alteration of heart abnormalities could be expected even in well chelated patients by echocardiography.
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