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Articles by Pradeep Kumar
Total Records ( 10 ) for Pradeep Kumar
  R.K. Goyal , R.T. Patil , A.R.P. Kingsly , Himanshu Walia and Pradeep Kumar
  Aonla is an important fruit crop indigenous to Indian sub-continent, which can be grown successfully in dry and neglected regions. The area under aonla has been expanding rapidly in the last couple of years. The growing popularity for alternate medicines, health foods and herbal products are enhancing the requirement for aonla fruit. The raw fruit, due to its high acidic nature and astringent taste, is unacceptable to consumers. The chemical composition of aonla fruits is influenced by environmental factors. Aonla fruit is highly nutritive with a great medicinal use and the richest source of vitamin C. The pulp of fresh fruit contains 200-900 mg of vitamin C. As aonla fruits are highly perishable in nature, its storage is very limited. The main objective of the review is to highlight its uses, existing processing methods and their limitations and further propose to develop pilot plant for aonla processing.
  Pradeep Kumar , Kumari Sunita and D.K. Singh
  Background and Objective: Fasciolosis is an endemic disease that causes severe economic conditions and affecting cattle populations even the human. The control of snail population is major tool in reducing the incidences of fasciolosis. The present study was designed for studying the effect of dried root powder of Potentilla fulgens (P. fulgens) use as molluscicides against vector snail Lymnaea acuminata (L. acuminata). Materials and Methods: Toxicity experiment of different organic extracts and column purified of P. fulgens was continuously observed for 96 h at different concentration. Mortality was observed for 24, 48, 72 and 96 h. Six aquariums were setup for each concentration. The control group animals were kept in the equal volume of water under similar conditions without treatment. Mortality of snails was recorded at interval of 24 h each up to 96 h by using POLO computer programme. Results: The dried root powder of P. fulgens at 96 h LC50 against L. acuminata was 133.62 mg L–1. Among different organic extracts, ethanol extract was more toxic than other organic extract. The ethanol extract of P. fulgens was more toxic (24h LC50-108.65 mg L–1) against L. acuminata. The 96 h LC50 of column purified fraction of dried root powder of P. fulgens was 28.69 mg L–1. Conclusion: The present study showed that the product of P. fulgens has potent molluscicidal activity. The product of P. fulgens may be used as potent molluscicides.
  Pradeep Kumar , Kumari Sunita and Dinesh Kumar Singh
  Background and Objectives: Snail Indoplanorbis exustus is an intermediate host of liver fluke. The control of snail population below threshold levels is major tool in reducing the incidences of fasciolosis. The present research was designed for studying the effect of dried root powder of Potentilla fulgens and their different products use as molluscicides against host snail I. exustus. Materials and Methods: The molluscicidal studies of different organic extracts and column purified fraction of P. fulgens were continuously observed for 96 h at different concentration. Mortality was observed for 24, 48, 72 and 96 h exposure. Six aquariums were setup for each concentration. The control group animals were kept in the equal volume of water under similar conditions without treatment. Results: The dried root powder of P. fulgens at 24 h and 96 h LC50 against I. exustus was 170.33, 140.29 mg L1, respectively. Among different organic extracts, ethanol extract was more toxic than other organic extract. The ethanol extract of P. fulgens was more toxic (24 h LC50-112.75 mg L1) against I. exustus. The 24 h and 96 h LC50 of column purified fraction of dried root powder of P. fulgens was 55.63 and 33.75 mg L1, respectively. Conclusion: The present study revealed that the different product of P. fulgens has potent molluscicidal activity and their product may be used as potent source of molluscicides.
  Pradeep Kumar , Ashok Kumar Misra and Dinesh Raj Modi
  Mango (Mangifera indica L.) occupies a pre-eminent place amongst fruit crops in India and is acknowledged as ‘King of fruits’ in the country. Malformation is the most threatening malady that causes great economic loss and limits the mango production in India and among tropical and subtropical countries around the globe. Floral malformation, in contrast to vegetative one, is very virulent and can cause the loss of the entire crop. Affected panicles either do not set fruit or abort fruit shortly after they have set; yields can be reduced by as much as 50-80%. Mango Malformation Disease is a fungal disease of mangoes caused by Fusarium species Fusarium moniliforme var. subglutinans. Mango is the only known host of the disease. Numerous studies on physiological, fungal, acarological, nutritional aspects have attempted, still the nature of the disorder is not fully understood. Keeping in view the seriousness of the problem, the present review explores out to establish a suitable genetic base, indicating the degree of resistance against malformation in different mango cultivars grown under open, natural field infection conditions. Disease management practices through various approaches.
  Satyendra Pratap Singh , Pradeep Kumar , Rajiv Manohar and J.P. Shukla
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  Pradeep Kumar , Satyendra Pratap Singh , Rajiv Manohar and J.P. Shukla
  The moisture dependent electrical properties of medicinally and nutritionally important Poppy seed have been reported in the present paper. The dielectric constant, dielectric loss and conductivity have been measured for Indian poppy seed over the temperature range 15-45°C at varying frequency i.e., from 5 KHz to 10 MHZ. The measurements have been carried out using electrical impedance spectroscopy. The electrical properties were found to increase with increases in moisture content. The electrical properties for non-viable seed (Dead seed) have also been measured and compared with the properties of viable seeds for different moisture levels. This comparison suggests that dialectic constant could be taken as an indicator of viability of seeds.
  R.K. Gupta , Pradeep Kumar , Alka Sharma and R.T. Patil
  Kinetics of color changes of aonla (Emblica officinalis) shreds were investigated using objective colorimetric measurements during drying with different blanching treatments. Kinetic parameters chroma, hue, total color difference, and browning index for the color change were determined using Hunter L, a, b values. The drying process changed all three color parameters (L, a, b), causing a color shift towards the darker region. Parameters L and b decreased and a-value increased during drying. The reaction associated with color change followed zero-order reaction kinetics. The minimum change was observed in the KMS (potassium metabisulphite) blanched shreds.
  Sunil Kumar Mishra , Bhoosan Yadav , Prabhat Upadhyay , Pradeep Kumar , Chandrashekhar Singh , Jyoti Dixit and Kavindra Nath Tiwari
  Background and Objective: Around 80% people are suffering from central nervous system (CNS) disorder and epilepsy, where most of the patients do not get adequate treatment. Management of epilepsy through synthetic drugs exhibit some side effects and may cause neurological changes. The aim of present study was to examine the Luffa cylindrica entire fruit alcoholic extract for polyphenol profiling, antioxidant and anti epileptic activity followed by biochemical and oxidative stress study and report a safe natural source for the management of epilepsy. Materials and Methods: The prepared extracts were detected in positive and negative mode of UPLC-MS/MS study followed by antioxidant activity through, 1,1-Diphenyl-2-picryl hydrazyl (DPPH) (227.19±0.84), superoxide dismutase (SOD) (2386.03±0.66) and lipid peroxidation (LPO) (226.14±1.38). The same extract was studied for diazepam induced sleep, pentylenetetrazole induced (PTZ) and maximal electroshock (MES, 70 mA) induced convulsion in wistar rat. Oxidative stress and cholinesterase activity of brain tissue was studied by estimating reduced glutathione and lipid peroxidation, total protein in both convulsive models. The changes at cellular level in rat brain histopathology were examined in microscope. Results: The study revealed the presence of total phenol (195.21±3.42 μg mL–1) and flavonoid (641.25±0.24 μg mL–1) and specifically 16 compounds i.e., hyperoside, kaempferol, acacetin, vitexin, leotiolin etc. were identified through LC-MS. The extract (400 mg kg–1) was found potentially active (p<0.05) in all the anticonvulsant study but less than the standard (phenytoin and diazepam). Minimal changes were observed in the extract (400 mg kg–1) and standard drug. Conclusion: Luffa cylindrica is using regularly in daily life as vegetable may be good source of potential antioxidant and anti epileptic activity. The alcoholic entire fruit extract showing the presence of phenolics and flavonoids suppose to be effective for the anti epileptic activity. However, further studies still needed to be carried on the extract for constituent specifically for the reported activity.
  Preetee Jaiswal , Pradeep Kumar , V.K. Singh and D.K. Singh
  Areca catechu is a species of palm grown mainly in Asian countries for seed crop. The chemical constituents of A. catechu have been investigated for anti-nematodal/helmintic, antioxidant, anti-venom, modulation of phagocytosis, effect on sperm motility/catecholamine release, as immunosuppression, management of psychiatric disorder and Alzheimer’s disease. Recent studies have revealed strong molluscicidal activity of A. catechu against harmful snails for the control of fascioliasis. Despite its laboratory studies on nematocidal/helmintic/molluscicidal activity of A. catechu. More field studies are recommended for effective control of these pests. Alkaloid arecoline is the major constituents of A . catechu for most of their biological effects. A. catechu deserves more attention by scientific community and health experts to explore its full range of benefits in welfare of mankind. Adverse effects of oral ingestion of A. catechu, causing Oral Submucous Fibrosis (OSF), oral submucous cell carcinoma should be taken in consideration, while their use is recommended in solving different health problems.
  Pradeep KUMAR , S.P. SINGH , K. SHRIKANT and D. MADHUKAR
  Food safety is of great importance to all involved in the food chain. The problem of pesticide residues is one of the concerns for the consumers. In the present study, 254 buffalo liver tissue samples were collected from 4 slaughterhouses and analyzed both qualitatively and quantitatively for the presence of chlorpyrifos residues. The samples were processed by extraction with acetonitrile followed by sonication and liquid-liquid partition. The extracts were cleaned up by performing alumina column chromatography. Chlorpyrifos residues in the samples were detected and quantified by employing high performance liquid chromatography. High performance liquid chromatography (HPLC) was performed by using the isocratic mobile phase, consisting of acetonitrile and water at a ratio of 67:33 with a flow rate of 1 mL/min and a run time of 18 min. The detection wavelength was set at 202 nm with 360 nm as the reference wavelength. Chlorpyrifos residues were detected in 9.05% of the samples. Of these, only 0.78% of the liver samples were found to exceed the Codex maximum residue limit (MRL) for chlorpyrifos.
 
 
 
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