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Articles by Poonam Sharma
Total Records ( 3 ) for Poonam Sharma
  Ram Sewak Kachhi , Vikas Kumar Saket , Poonam Sharma and Pranveer Singh
  Background and Objective: Tribals in Amarkantak region of Madhya Pradesh district owing to abject poverty, illiteracy avoid taking modern allopathic treatment for tuberculosis and resort to occult/hokum that aggravates the disease making them potential reservoir of infection. Materials and Methods: Present study has employed the novel concept of combining the best of modern TB diagnostics with traditional herbal medicine system for TB treatment. The study has enrolled over hundred cases of uncured TB and also the relapse cases across different age groups, gender and status over the period of 2 years. Results: The outcome has validated the efficiency of proposed model of treatment as patients were completely cured of TB without significant relapse cases. Additionally, it has multitude of benefits including economy of cost involved and lack of any potential side effects. Traditional system of medicine has proven itself to be a robust system for TB treatment with multitude of benefits. Conclusion: The findings from many more similar studies may pave the way for adopting such model of treatment. This will ease the economic burden on the government exchequer by reducing the cost of the treatment and will increase the cultivation and conservation measures of medicinally important plants.
  Poonam Sharma
  Problem statement: In this research, we studied parametric p-valent meromorphic functions Pαf by considering two classes Mαp(Β) and Mαp(λ,A). Approach: With the help of Jack’s Lemma an inclusion relation for the class Mαpwas obtained and it is shown that this class is closed by an integral operator Ic. Results: A subordination result for the class Mαp(λ,A)was proved. Consequences of main results with the results for special values of the parameter α were discussed. Conclusion/Recommendations: Our results certainly generalized several results obtained earlier as well as generate new results.
  Rambir Singh , Aarti Seherawat and Poonam Sharma
  The aim of the study was to evaluate the antidiabetic effect of Momordica dioica fruit extracts in alloxan induced diabetic wistar rats. Aqueous extract of Momordica dioica (AEMD) showed maximum fall (52.8%) in 0 to 1 h Fasting Blood Glucose (FBG) in Glucose Tolerance Test (GTT) compared to hexane (39%), chloroform (37.2%) and ethanol (37.7%) extract in normal healthy rats. Since AEMD exhibited maximum hypoglycaemic activity as compared to other extracts, it was further studied for antidiabetic effect in diabetic rats. The oral Effective Dose (ED) of AMED was 200 mg kg-1 body weight which produced a fall of 57.5% (p<0.001) in diabetic rats. The 200 mg kg-1 body weight AMED once daily for 21 days reduced the elevated Blood Glucose (BG) by 64.8% (p<0.001), Post Prandial Glucose (PPG) by 76.9% (p<0.001) and glycosylated hemoglobin (HbA1c) by 37.6% (p<0.001). Urea, creatinine and urinary sugar, total protein, AST, ALT, alkaline phosphatase and bilirubin activities were also reduced after AEMD treatment in diabetic rats. Above 3 g kg-1 b.wt was Lethal dose of AEMD i.e., 15 times of ED indicating high margin of safety. Our study suggests possible use of aqueous extract of fruits of M. dioica for the management of diabetes mellitus.
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