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Articles by Peyman Mikaili
Total Records ( 5 ) for Peyman Mikaili
  Jalal Shayegh , Peyman Mikaili , Jalil Dolgari Sharaf and Ali Rastgu
  Antibiotic resistance pattern of ovine and bovine Pasteurella multocida were evaluated to 16 antimicrobial agents by the disc diffusion method. About 75 and 42.85% of strains were resistant to lincomycin among ovine and bovine isolates, respectively. High level of penicillin resistance from bovine isolates is noticeable. Also, the antibiotic resistance patterns show the slight increase in resistance of other antibiotic and it is necessary to check antibiotic resistance patterns of P. multocida time to time in order to make effective decisions in treatment programming against animal disease.
  Jalal Shayegh , Peyman Mikaili , Jalil Dolgari Sharaf and Ali Rastgu
  Antibiotic resistance pattern of ovine and bovine Pasteurella multocida were evaluated to 16 antimicrobial agents by the disc diffusion method. About 75 and 42.85% of strains were resistant to lincomycin among ovine and bovine isolates, respectively. High level of penicillin resistance from bovine isolates is noticeable. Also, the antibiotic resistance patterns show the slight increase in resistance of other antibiotic and it is necessary to check antibiotic resistance patterns of P. multocida time to time in order to make effective decisions in treatment programming against animal disease.
  Seyyed Javad Mousavi , Peyman Mikaili and Karim Yazdani
  One of the surgical emergencies is vascular trauma which it should be managed by vascular surgery as soon as possible. The delay in referring the patient to surgery ward will cause the involved organ to be failed. In general, vascular traumas are divided into two types of penetrating and blunt traumas. The aim of this study is evaluating the profile of indications of vascular surgeries in northwest Iran. In this study, during 3 years, 33 patients were referred to this center and underwent vascular trauma surgery. The mean ages of involvement were between 20-40 years old. About 30 patients (90%) were male and 3 cases (10%) were female. The high rates of trauma were due to blunt type and the car accident was in the first rank. The highest rate of involvement occurred in posterior limb (20 cases). Of 33 patients with vascular trauma, 14 cases underwent vascular surgery in 6 h after the trauma. The rest referred and underwent surgery with >6 h delay. According to the results of this study, the researchers showed that the delay in referring the patient to surgery ward will cause the involved organ to be failed in higher rate in comparison to the rest.
  Ali Asghar Hemmati , Ardeshir Arzi , Neda Karampour Sistani and Peyman Mikaili
  Several in vivo studies have documented that supplementation with pomegranate fruit extract inhibits inflammatory symptoms. In the present study, the anti-inflammatory properties of total hydro-alcoholic extract isolated from pomegranate seed were investigated in formalin-induced rat paw edema. The studied male Wistar albino rats (n = 30) were divided into 5 groups. Inflammation was created by injection of formalin (2.5%) intraplantarily. Then different doses of extract (100, 200, 400 mg kg-1) were injected in 3 groups, indomethacin (5 mg kg-1) was injected in 4th group and control group received 5 mL of normal saline intraperitoneally. About 1-3 h after injection of the extract, indomethacin and saline, the volume of paw was measured in all groups by plethysmometer. The results showed hydro-alcoholic extract of pomegranate seed has dose-dependent anti-inflammatory effect and the highest anti-inflammatory effect was observed in the dose of 400 mg kg-1.
  Majid Mohajer Milani , Abbas Sahebghadam Lotfi , A. Mohsenifar , Peyman Mikaili , Nahid Kamelipour and Jeyran Dehghan
  Organophosphorous Compounds (OPC) are one group of ester and amide or derivatives of toxic thiol-phosphoric compounds widely used to control insects and pests. Such compounds cause the deactivation of acetyl cholinesterase enzyme and create complications in organisms. Wild-type Organophosphorus Hydrolase (OPH) is used for the identification and detoxification of organophosphorus compounds. Immobilization of OPH enzyme on various levels is one of the most effective methods to develop identification and detoxification. As a biopolymer including reactive amine and hydroxyl groups and due to the amine groups as cationic polyelectrolyte, chitosan is particularly important and has many applications, especially in the field of immobilization. In the present study, OPH enzyme was immobilized on chitosan beads and glutaraldehyde was used as cross-linker. Binding the enzyme to chitosan beads was confirmed by Fourier Transform Infrared (FTIR) spectroscopy system and the assessment of its activity was also confirmed. The thermal stability of free and immobilized enzymes was measured in the temperature range of 25-80°C. The pH stability of free and immobilized enzymes was examined at 2-12 pH and the assessment of the reusability of immobilized enzyme was also investigated. The results showed that the thermal stability and pH of the immobilized enzyme was more than that of the free enzyme. Evaluating the reusability of immobilized enzyme indicated that the immobilized enzyme can be applied at least three times without decreasing its activity. The results of this study show the positive role of immobilizing the enzyme in increasing its activity and stability. Immobilization also increases reusability of immobilized enzyme and is economically affordable.
 
 
 
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