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Articles by Peng Wang
Total Records ( 9 ) for Peng Wang
  Jing Wang , Li-Jun Shi , Peng Wang , Zhan-Zhong Zhao , Miao-Miao Gong , Gang Li , Wei-Feng Yuan and Hong-Fei Zhu
  In order to investigate the new strains circulating in Beijing, 24 positive samples of CPVs were isolated from Beijing of China between 2009 and 2011 and the sequences of the main capsid protein VP2 were obtained. These sequences were analyzed in comparison with the sequences of 29 other strains of CPV from GenBank. Two types of CPV, including CPV-2 and CPV-2a were detected and CPV-2a (with Ala297 mutation) was predominant in Beijing and 4 strains CPV-2a types were found to carry the amino acid substitution Ala440. The unique Ile324 mutation in the VP2 of Beijing CPV isolate was detected as compared with a Tyr324 in the VP2 of the reference CPV strains. A phylogenetic tree was constructed from the VP2 genes. These results showed that most of the isolated Beijing strains classified in a cluster Chinese field isolates which were distinct from American and Italian isolates.
  Yongbin Lai , Bo Wang , Xiu Chen , Yinnan Yuan , Lei Zhong , Xing Qiao , Yuqi Zhang , Menghong Yuan , Junfeng Shu and Peng Wang
  Palm oil and rapeseed oil were transesterified with methanol using NaOH as catalyst to obtain Palm Methyl Ester (PME) and Rapeseed Methyl Ester (RME). To investigate the combustion characteristics of PME and RME, the chemical composition was analyzed by Gas Chromatography-Mass Spectrometry (GC-MS); fuel properties including density, kinematic viscosity, flash point, cold filter plugging point, sulfur content and copper strip corrosion were characterized; combustion experiment was performed in the furnace of Thermogravimetry-Differential Scanning Calorimetry (TG-DSC) simultaneous thermal analyzer. Combustion characteristic index was put forward for describing biodiesel combustion characteristic. The study showed that the biodiesel was mainly composed of Fatty Acid Methyl Esters (FAMEs): C14:0-C24:0, C16:1-C22:1, C18:2 and C18:3. The Saturated Fatty Acid Methyl Esters (SFAMEs) content of PME and RME were 35.86 and 14.69 wt.%, respectively. Biodiesel is oxygenated fuel had a good burnability. Combustion characteristic indexes of PME, RME were 4.97E-05 and 3.65E-05, respectively. The combustion characteristic had relation to chemical composition. The combustion characteristic of biodiesel was better with increasing SFAMEs length of carbon-chain, was poorer with increasing Unsaturated Fatty Acid Methyl Esters (UFAMEs) and unsaturated degree. The combustion characteristic of PME was better than that of RME.
  Guoyin Zhang , Bin Tang , Peng Wang , Yanxia Wu and Xinyu Zhang
  In-net caching is an important part of the content centric network architecture. So far, the default "Leave Copy Everywhere (LCE)" caching policy will cache all content without distinction, lead to a large number of cache content redundant in the nodes of network. Due to the limitation of node cache size, redundant reduced the verity of cache content cached in network, result in bad utilization of cache space. To boost the performance of the cache, many improved mechanisms have been put forward, including LCD, MCD and ProbCache caching policies. This article respectively experimented the LCE, LCD, MCD and ProbCache algorithm, judging by standards like content response delay, network link load, server stress, evaluation index, analyzed factors, such as network topology, content popularity and cache space, have what kind of effect on these policies’ performance.
  Peng Wang , Shu-shan Li and Xiao-hu Wang
  In arthritis, osteoarthritis (OA) is very common and is a progressive chronic illness of the joint impairing its function and thereby eventually affects the quality of patient’s life. Currently employed therapeutic drugs aim to alleviate OA symptoms, however it poses adverse effects. Hence, identification of novel compounds that could effectively block the progression of OA and as well reduce symptoms is of high clinical value. This investigation was carried out to assess the effects a flavonoid, myricetin on the IL-1β induced SW1353 cells. The SW1353 cells were subjected to myricetin treatment at 75, 150 or 300 μg for 3 h before IL-1β stimulation at 5 ng mL–1 for 24 h and the treatment with myricetin significantly improved the cell viability of IL-1β-induced SW1353 cells and reduced the levels of PGE2 and NO. The results suggest the anti-inflammatory effects of myricetin. In addition, myricetin effectively supressed matrix metalloproteinases (MMPs-MMP1, 3 and 13) expression and also the expression of mitogen activated protein kinases (ERK, JNK and p38 kinase). The activation of NF-κB and AP-1 (transcription factors) were regulated by myricetin. Further, JAK2/STAT1 signalling was modulated effectively on myricetin treatment at all the three tested doses in a concentration dependent manner. Myricetin thus by targeting major pathways in pathogenesis of OA could be explored further for its therapeutic potential in OA treatment.
  Peng Wang , Teng-Fei Long , Li-Ping Wang and Jie Song
  Background and Objective: Epidemiological studies have shown admiring protective roles of phytochemicals on peripheral nervous system, while the prevalent use of hypotensive drugs directly impacts normal functioning of the nervous system. Hence, the present study was assessed the synergistic role of Asiatic Acid (AA) and Madecassic Acid (MA) against the antioxidant deficit induced by the metoprolol tartrate. Materials and Methods: Wistar male rats (150 mg kg1) were divided into 4 groups. Group 1 as control with no treatment, group 2 rats with metoprolol tartrate (150 mg kg1/day, orally), group 3 rats pre-treated with AA (50 mg kg1, IP) and MA (30 mg kg1, IP) for 2 weeks prior to metoprolol tartrate and group 4 with AA and MA combined as drug control for 28 days. Blood pressure (BP), heart rate (HR) and other antioxidant parameters were monitored and the blood samples were collected for endocrine and biochemistry analysis. Results: Metoprolol administration demonstrated a significant reduction in body weight, systolic BP, heart rate and food intake, while the levels of lipid peroxidation was increased significantly compared to control rats. Also, a significant decrease (p<0.01) in the antioxidant levels such as; SOD, catalase, glutathione peroxidase, reduced glutathione were evidenced in metoprolol group. On the other hand, the neuronal markers enzyme acetylcholinesterase were reduced while the activity of Nitric Oxide Synthase (NOS), Cytochrome P450 Reductase (CPR) and Carbonic anhydrase were increased in metoprolol group compared to control. However, rats received AA and MA pre-treatment elicited the improved antioxidant enzymes with restored physiological parameters, food intake and reduced the marker enzymes activity. Conclusion: The results of present study demonstrated the protective role of AA and MA against antioxidant deficit induced by the metoprolol tartrate by improving the physiological functions.
  Guiyun Huang , Tonggeng Guan , Peng Wang and Shourong Qin
  Background and Objective: Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affected the joints. The aim of the current study was to investigate the anti-arthritic and anti-inflammatory effect of baicalein against complete Freund’s adjuvant-induced arthritis via alteration of inflammatory reaction. Materials and Methods: Complete Freund adjuvant (CFA) was to induce arthritis in the Wistar rats and rats were divided into a different group and received the oral administration of baicalein until 28 days. The paw edema, body weight and arthritic score were estimated at a regular time interval. At the end of the experimental period, antioxidant, hematological and pro-inflammatory cytokines were estimated. Results: Baicalein treated rats showed the down-regulation of paw edema, arthritic score and significantly (p<0.001) increased the body weight. Baicalein treatment significantly (p<0.001) modulated the antioxidant, hematological parameters and pro-inflammatory cytokines. Baicalein attenuated the effect of CFA on bone surface area, bone volume and trabecular thickness. Baicalein significantly (p<0.001) reduced the inflammation, cartilage surface erosion, chondrocyte death and bone erosion. Conclusion: Baicalein indicated the beneficial effect against the CFA induced arthritic rats via pro-inflammatory cytokine mechanism.
  Xiaoliang Zhou , Kening Sun , Yan Yan , Shiru Le , Naiqing Zhang , Wang Sun and Peng Wang

The silver electric adhesive doped with Al2O3 ceramic particles is used as sealing material for planar solid oxide fuel cell (SOFC). The sealing temperature of this sealing material is 600 °C with the heating rate of 2 °C min-1, and the minimal leak rate ranges from 0.030 sccm cm-1 to 0.040 sccm cm-1. When doping 15 mass% Al2O3 ceramic particles into this sealing material, the thermal expansion coefficient of this material decreases from 20 ppm K-1 to 15 ppm K-1, which improves the thermal matching performance and the long-term stability of the material significantly. When using the gradient sealing method with the pure silver electric adhesive and the silver electric adhesive doped with Al2O3 ceramic particles to seal the interface of Ni-YSZ/SUS430 in the simulating cell, the minimal leak rate of 0.035 sccm cm-1 is obtained for the cell. Furthermore, the simulating cell sealed with the compound silver electric adhesive presents good heat-resistant impact ability. Therefore, this compound sealing technique is a very promising sealing method for SOFC.

  Jinchao Zhang , Cuilian Liu , Jing Sun , Dandan Liu and Peng Wang
  The effects of water extract of Cajanus cajan (Linn.) Millsp. (Leguminosae) leaves (WECML) on the osteogenic and adipogenic differentiation of mouse primary bone marrow stromal cells (BMSCs) and the adipocytic trans-differentiation of mouse primary osteoblasts (OBs) were studied. The results indicated that WECML promoted the proliferation of BMSCs and OBs at most concentrations. WECML promoted the osteogenic differentiation and formation of mineralized matrix nodules of BMSCs at concentrations of 0.1, 1, and 10 μg/mL, but inhibited the osteogenic differentiation and formation of mineralized matrix nodules of BMSCs at concentration of 0.01 μg/mL. WECML inhibited the adipogenic differentiation of BMSCs and adipocytic trans-differentiation of OBs at concentrations of 0.001, 0.1, 1, 10, and 100 μg/mL, but had no effects at concentration of 0.01 μg/mL. The results suggest that WECML has protective effects on bone and these protective effects may be mediated by decreasing adipocytic cell formation from BMSCs, which may promote the proliferation, differentiation, and mineralization function of OBs. The defined active ingredients in the WECML and the active mechanism need to be further studied.
  Xianzhu Xu , Peng Wang , Rong Hao , Meina Gan , Fuxing Sun and Guang-shan Zhu
  A novel zinc diphosphonate, Zn[HO3PCH2(C6H4)CH2PO3H] (1) was synthesized from tetraethyl para-xylylenediphosphonate, Et2O3PCH2C6H4CH2PO3Et2, and Zn (AcO)2·2H2O under solvothermal conditions. The structure of compound 1 was determined by single-crystal X-ray diffraction, which reveals that the structure crystallizes in the monoclinic space group C2/c (No. 15), with a = 22.4844(19) A, b = 6.4361(5) A, c = 8.1194(7) A, β = 102.595(2)°, V = 1146.70(16) A3, T = 298(2) K, Z = 8. The novel three-dimensional (3D) construction is simply built up from linear inorganic chains of corner-sharing four-rings of tetrahedral [ZnO4] and [PO3C] which connected adjacent chains by the organophosphorus ligand para-xylylenediphosphonate. The framework has 10 A x 4 A (containing the van der Waals radii of atoms) channels running along the b-axis.
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