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Articles by P. Thirugnanasambantham
Total Records ( 3 ) for P. Thirugnanasambantham
  Ganesh, R. , S. Viswanathan , P. Thirugnanasambantham , E. Ayisvren and Anoop Austin
  Arogh, a polyherbal formulation was found to be effective in treating hypercholesteremia in rats. Increase in body weight, total cholesterol, triglycerides, LDL and VLDL observed in cholesterol fed animals were attenuated by treatment with Arogh. It also reversed the histopathological changes produced in various organs by cholesterol supplementation. Liver and kidney function tests were not altered by either cholesterol or Arogh treatment. Arogh exerts a significant hypolipidemic effect, prevents atherosclerotic changes and reduces obesity in experimental animals.
  G. Senthilvel , M. Jegadeesan , Anoop Austin , P. Thirugnanasambantham , E. Mayisvren , M. Balasubramanian , N. Narayanan and S. Viswanathan
  Diarun plus was evaluated for its therapeutic antihyperglycemic activity in streptozotocin-induced diabetes in animal models. It was effective in controlling hyperglycemic status in rats and mice. The drug (500 mg/kg) showed significant antidiabetic property as judged by serum glucose levels. However, it did not significantly influence the levels of serum insulin in both diabetic and normoglycemic rats. This is a promising drug to develop standardized phytomedicine for diabetes mellitus. The findings suggest that it can be considered as a therapeutic agent, wherever elevated glycemic status is observed.
  Anoop Austin , G. Senthilvel , P. Thirugnanasambantham and E. Mayisvren
  Hyperlipidemia is one among the risk factors affecting normal health. Though various hypocholesteremic agents are available, they are having their own limitations. Arogh is a scientifically validated polyherbal Instant Formulation indicated for hypercholesteremia, stress, cardiac ailments and Obesity. This study is focused as a randomized clinical study in treating hyperlipidaemia. Arogh was found to effectively reducing total cholesterol, triglycerides and LDLc levels and increased TC/HDLc ratio HDLc levels. This helps preventing atherosclerosis and reduces the risk of CHD.
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