Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

S. A Quezada, T. R Simpson, K. S Peggs, T Merghoub, J Vider, X Fan, R Blasberg, H Yagita, P Muranski, P. A Antony, N. P Restifo and J. P. Allison

The Journal of Experimental Medicine 207 ( 3 ): 637 - 650 , 2010