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Articles by Ozgur Kaynar
Total Records ( 3 ) for Ozgur Kaynar
  Fatma Kaynak Onurdag , Tuncer Degim , Zelihagul De im , Ismail Kutlu , Ozgur Kaynar , Gulsen Gunes and Ufuk Abbasoglu
  Brucellosis is an important zoonotic disease and the prevention is made by vaccination of animals. For ewes Brucella melitensis REV-1 live attenuated vaccine is widely used but because of some risks such as being infected during the vaccination, re-infection of animals, a new vaccine with less side effect is need to be improved. In this study it was aimed to determine a strong humoral immune response by encapsulating the Brucella outer membrane antigens with the optimum liposome formulation and the statistical analyses showed that the Brucella outer membrane extract encapsulated with liposome can evoke humoral immune response better than live attenuated B. melitensis REV-1 vaccine in mice.
  Arma an Colak , Ozgur Kaynar , Yunusemre Ozkanlar , Fikrullah K sa and Armagan Hayirli
  The periparturient period is characterized by negative energy balance because feed intake gradually decreases prior to parturition and increases at a slower rate than milk production. This is one of the contributing factors to occurrence of other peripartum period health problems including mammary gland and reproductive tract infections. Especially high-producing dairy cows are prone to ketosis and infectious diseases, which adversely affect profitability of dairying. To maintain plasma concentration above 3 g mL -1 at parturition, vitamin E supplementation during the transition period benefits to immune system via improving neutrophil activity and consequently reduces risk for mastitis and retained placenta. Ketone bodies also impair immune function. However, improvement in immune function in cows with ketosis in response to vitamin E supplementation remains to be investigated.
  Ozgur Kaynar , Armagan Hayirli , Ahmet Yildiz , Zafer Okumu , Fikrullah Kisa , Emel Banu Buyukunal Bal , Harun Polat and Fuat Erdem
  In this experiment, 18 female and 18 male Sprague Dawley rats were utilized to evaluate physiological and biochemical traits. Rats were fed to ad libitum consumption of the conventional diet and housed in cages separately by gender at density of 160 cm2 per rat from 3 to 10 weeks of age. At the end of the experiment, body weights were measured for growth, blood samples were collected for metabolic profile and hemogram and then rats were euthansized for organ development. After log transformation of blood cell data, all response variables were subjected to t-test for gender comparison and normality and correlation tests for generation of reference values and determination of autocorrelations. Growth and organ development were greatly affected by gender. However, gender effect on weights of organs altered when weights were expressed in proportion to body weight. Differences in blood chemistry by gender were in agreements with those in weights of organs. White blood cell counts were not different. Erythrocyte and related hemogram variables differed by gender. In conclusion, variations and differences in biochemical and physiological traits by gender should be taken into consideration for future investigations coping with medical and nutritional issues.
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