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Articles by Olukanni Olumide David
Total Records ( 1 ) for Olukanni Olumide David
  Adeyanju Moronke Muinat , Fasanya Temitope Abigail , Olawoore Oluwapelumi Emmanuel , Salau Tioluwani Bamidele , Adeniji Paulina Olufunke , Otuechere Chiagoziem Anariochi , Olukanni Olumide David and Salau Bamidele Adewale
  Background and Objective: Sucrose has been implicated in the etiology of many diseases with pronounced effects on various organs, such as liver, kidney and brain to mention but few. However, its effect on reproductive organ appears data-sparse. The study investigated the effect of long term feeding of sucrose diet on the testes of male albino rats. Materials and Methods: Twenty four male albino rats grouped into 4 with varying concentrations of sucrose supplying energy at 0% (control), 10% (SUD 10%), 20% (SUD 20%) and 30% (SUD 30%), respectively. Animals were fed for 6 months and the testes were harvested for assessment of lipid profiles and oxidative stress parameters. Results: Substantial increase (p<0.05) was observed in triglycerides, total, LDL and VLDL cholesterols while decrease (p<0.05) was observed in HDL cholesterols as sugar content of diet increases. Whereas significant decrease was observed (p<0.05) in glutathione-s-transferase (GST), superoxide dismutase (SOD), catalase (CAT) and reduced glutathione (GSH) levels, substantial increase (p<0.05) was observed in malondialdehyde (MDA), an index of lipid peroxidation. Conclusion: In conclusion, we opined that the alteration in antioxidant status, lipid peroxidation and lipid profile may adversely affect reproductive functions in male albino rats fed long term sucrose diet.
 
 
 
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