Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Articles by O.O. Akande
Total Records ( 1 ) for O.O. Akande
  A.M. Akingbade , L.C. Saalu , O.O. Oyebanji , D.A. Oyeniran , O.O. Akande and G.G. Akunna
  This study evaluates the testicular degeneration induced by Rhodinol-based incense using testicular histology, sperm characteristics, as well as testicular oxidative status bio-markers. Twenty four male adult albino rats (10-12 weeks old) weighing 200-230 g were divided into four groups (A, B, C and D) of six rats each. Group A served as the control group and the animals in this group were exposed to 1 g of natural solid air freshner. Groups B, C and D, were exposed to 1, 2 and 3 g of rhodinol-based incense smoke, respectively for 30-40 min every day for 62 days. All the exposures were via whole body inhalation. The animals were sacrificed 24 h after. The results obtained from this study showed a significant (p<0.05) decrease in the gross anatomical parameters of absolute and relative testicular weights in rats exposed to 2 g and 3 g rhodinol based incense when compared to the control group. The rhodinol-based incense exposed groups of rats also demonstrated a reduction of basal seminiferous epithelia, testicular atrophy, germinal aplasia and hypo-spermatozoa formation. Furthermore, there was a statistically significant (p<0.05) decrease in sperm count, sperm motility, normal sperm morphology and a significant (p<0.05) increase in total abnormal sperm morphology in group of animals exposed to 2 and 3 g rhodinol-based incense when compared to the control group. In addition, groups of animals exposed to 2 and 3 g rhodinol-based incense demonstrated a derangement in their oxidative status when compared to the control group as evidence by the significant (p<0.05) decreased in activities of superoxide peroxidase, catalase, glutathione, reduced glutathione and significant (p<0.05) increase malondialdehyde (a product of lipid perioxidation). Taken together, it was concluded that rhodinol-based incense produces testicular derangement in testicular histology, sperm parameters and oxidative status in albino rats. This derangement may be mediated at least in part through the oxidative pathway.
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility