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Articles by O.I. Oloyede
Total Records ( 2 ) for O.I. Oloyede
  B.T. Aluko , O.I. Oloyede and A.J. Afolayan
  This study assessed the polyphenolic contents and antioxidant activity of ethanol, butanol and ethyl acetate extracts of Ocimum americanum leaves using in vitro models. The ability of the extracts to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS●+), hydrogen peroxide (H2O2), Nitric Oxide (NO) and hydroxyl radical (OH) was investigated. The inhibition of lipid oxidation, reducing power, total flavonoids, phenols and flavonols contents of the extracts were also determined using spectrophotometric methods. The result revealed highest concentration of polyphenolic compounds in the ethanol extract followed by n-butanol while ethyl acetate extract contained the least concentration. Free radical scavenging potentials of the extracts were found to be proportional to their respective polyphenolic contents. This study provides evidence that O. americanum leaves contain biologically active components with effective antioxidant activity and thus could be used for the management of radical related diseases.
  O.I. Oloyede
  Perforated cowry shells (Cyparica samplometa) were tested for the presence of certain phytochemicals, minerals Proximate analysis were also determined. Cowry shells (dry weight) showed the presence of Alkaloid, Cardiac glycosides, Tannins and quinones. Chemical analysis revealed the presence of Calcium (91.3±0.45 mgl100g) and Iron (47.52±0.02 mg/100g) as well as Aluminum and Sodium in considerable quantities. Proximate analysis showed that it contained moisture content (0.22%), Ash content (76.30%), Crude fibre (7.27%), Crude protein (5.10%) carbohydrate (14.13%) and Crude fat (0.42%). The presence of some important phytochemicals and calcium in highest quantity explains the action of the cowry shells encountered in therapeutic uses and their involvement in pharmaceutical product. The extraction of bioactive agent of cowries shell is one of the most intensive area of natural product research.
 
 
 
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