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Articles by Nurul Absar
Total Records ( 7 ) for Nurul Absar
  M. Ullah , Fazlul Karim Chy , Subodh Kumar Sarkar , M. Khairul Islam and Nurul Absar
  Bitter gourd (Momordica charantia) were analyzed for their major nutrient contents as well as Vitamin C, minerals and phytochemical constituents. The selected varieties were Charantia C.B. Clarke, Muricata (Willd.), Hybrid green and Hybrid white karala. The result revealed the presence of nutrient constituent among the varieties comprising Total sugar (0.114±0.01% to 0.22±0.02%), Starch (0.74±0.01% to 5.3±0.04%), Total protein (1.17±0.01% to 2.4±0.02%), Fat (0.3±0.02 to 0.8±0.02%) and Vitamin C (9.41±0.26 to 13±0.57mg%). This vegetable is good source of minerals such as Mg, Ca, S and Cu. The fruits contained calcium (0.55±0.30 to 7.0±0.25 mg%) and sulpher (44.9±0.38 to 72.4±0.51 ppm). All the varieties were found to contain tannin, flavonoids, terpenoids, cardiac glycosides, triterpin and sterol, resin, amino acid and phenolic compounds except coumarin and free anthraquinone. Based on the findings from this study, bitter gourd (Momordica charantia), although a bitter known vegetables but has enormous nutritional potentials.
  Subodh Kumar Sarkar , Ujjal Sen , Monoranjan Dhar , Nurul Absar and M. Khairul Islam
  Although strawberry is produced mainly in the cold weather but recently it is a newly introduced crop in the subtropical country like Bangladesh by tissue culture technique. It is not only the excellent sources of Vitamin C, β-Carotene, dietary fiber and some other nutrients but it has also several medicinal importances for human health and nutrition as reported by researchers in different countries other than Bangladesh. The major nutrient contents as well as minerals and vitamins of two varieties, Varaity-1 (Long Conic) and Variety-2 (Globose Conic) of strawberries were analyzed. The result revealed the presence of nutrient constituent among the two varieties, Varaity-1 (Long Conic) and Variety-2 (Globose Conic) of strawberries comprising Total sugar (3.15±0.01 and 2.5±0.02%), Reducing sugar (0.0335±0.01 and 0.048±0.01%), Non-reducing sugar (3.12±0.01 and 2.4±0.01%), Starch (0.395±0.02 and 0.685±0.04%), Water soluble protein (0.785±0.01 and 0.986±0.01%), Total protein (1.2±0.02 and 1.5±0.02%), fat (0.4±0.01 and 0.6±0.02%), Vitamin C (116±0.32 and 179±0.52 mg%), Beta-carotene (3.71±0.25 and 4.15±0.30 μgm%) and minerals such as Magnesium (17.35±0.01 and 17.76±0.01 mg%), Calcium (6.40±0.20 and 11.36±0.40 mg%), Potassium (38.00±0.20 and 43.00±0.01 mg%), Copper (0.1365±0.02 and 0.0275±0.01 mg%), Iron (0.12±0.02 and 0.5415±0.01 mg%), Zinc (0.092±0.01 and 0.049±0.03 mg%), Phosphorous (0.718±0.01 and 0.627±0.02 mg%) and Sulphur (5.56±0.20 and 5.735±0.22 mg%), respectively. Results of present study suggest that Strawberry is a good source of sugar, anti-oxidants and minerals and among both the varieties, Variety-2 (Globose Conic) is rich of sugar, total protein, water soluble protein, Vitamin C, Beta-carotene, Magnesium, Calcium, Potassium, Iron and Sulphar. In this study, the aqueous extract of two varieties (Long Conic and Globose Conic) of strawberry was tested for anti-microbial activity by disc diffusion method and cytotoxicity by brine shrimp nauplii. From the results, it was found that the aqueous extract of both varieties of strawberry revealed anti-microbial activity against gram positive and gram negative bacteria. It was also found that the aqueous extract of two varieties of strawberry was not shown cytotoxic activity. Even though, the aqueous extract of two varieties of strawberry was not shown toxicity on brine shrimp nauplii but they are showing anti-bacterial activity against gram positive and gram negative bacteria. This result clearly indicates the presence of potent bioactive principles in this aqueous extract of both varieties of strawberry which suggests a need to isolate, purify and evaluate active constituents responsible for this anti-microbial activity.
  Tanzima Yeasmin , Abul KashemTang , Anowar Hossain and Nurul Absar
  Three lectins were extracted and purified from mulberry seeds i.e., MSL-1, MSL-2 and MSL-3.These lectins exhibited strong cytotoxic effect in brine shrimp lethality bioassay. The biological activities of the lectins MSL-1, MSL-2 and MSL-3 were studied after various physical and chemical treatments. The biological activities of the lectins were affected greatly with the changes of pH and temperature and the lectins showed maximum hemagglutinating activities around pH 7.2-7.6 and temperature 20-35°C. The biological activities of the lectins were abolished with the higher concentration of acetic acid and denaturants, guanidine-HCl and urea. The activities of all the three lectins were affected more pronouncedly by guanidine-HCl than urea. In the presence of metal chelator, EDTA and-SH group binding agent, HgCl2, the heamagglutinating activities of the mulberry seed lectins were destroyed completely while in the presence of Ca2+ salts that of the lectins were increased remarkably.
  Tanzima Yeasmin , Abul Kashem Tang , Anowar Hossain and Nurul Absar
  This study deals with the effect of different chemical modifying agents on the mulberry seed protein, namely MSL-1 and MSL-2, to obtain information on the structure-function relationship of these lectins. Mulberry seed lectins, MSL-1 and MSL-2, having specificity for D-galactose were subjected to various chemical modification in order to obtain information about the amino acid residues responsible for their carbohydrate binding property. The modifying reagents used are mild and very much selective for modification of specific groups. Modification of tyrosine, histidine and thiol, groups led to a complete or significant loss of their activities, indicating the involvement of these amino acid residues in the saccharide binding property of the lectins. However, modification of lysine, arginine and trypotophan residues had no such noticeable effect on the biological activities of these two lectins. These findings are very similar to those reported for other lectins that bind D-galactose and also fit the general trend in other lectins.
  M. Mahbubar Rahman and Nurul Absar
  The α-amylase from mango-pulp of Himsagar variety was purified by successive ion-exchange chromatography on DEAE-cellulose followed by CM-cellulose. The purified enzyme was found to be homogenous as judged by polyacrylamide gel electrophoresis. The molecular weight of a -amylase was estimated to be 54,500 by gel filtration and 55,200 by SDS-PAGE respectively. The enzyme showed the following characteristics : Neutral sugar content 4.8%, optimum pH 6.8, optimum temperature 37°C and Km value 0.33% against starch as substrate and absorption maximum at 279nm in aqueous solution. The activity of the enzyme was increased in the presence of metallic salts such as Ca2+, Mg2+ and Mn2+ while Fe2+, Zn2+ and Cu2+ inhibited the activities moderately. The effect of urea, guanidine-HCI and acetic acid on the activities of α-amylase were discussed.
  M. Ullah , Mir Showkat , Nazim Uddin Ahmed , Saiful Islam and Nurul Absar
  Momordica charantia L. fruits, leaves, seeds and roots are considered as valuable traditional medicine. It is considered antidotal, antipyretic, tonic, antispasmodic, mild hypotensive. It builds immunity, relieves fever and reduce cholesterol level. To give a scientific basis for medicinal usage of this medicinal plant, the fruit extract was evaluated for the analgesic and anti-inflammatory activities. In this study, the acute toxicity study, analgesic and anti-inflammatory activities of Momordica charantia L. fruit extract were evaluated in a series of in vivo assay. Acetic acid induced writhing test and tail immersion test in mice were used to study the analgesic effect, while the effect of the extract on acute inflammation was investigated by carrageenan-induced paw edema in rats. For phytochemical analysis in vitro assay were performed according to the slandered procedure. The oral administration of M. charantia extract upto 2 g kg-1 in mice was found to be safe The extract significantly (p<0.001) inhibited acetic acid induced writhing and tail-immersion test induced pain at dose 500 mg kg-1, p.o. The extract also produced a moderate anti-inflammatory activity which was found to be significant at all the doses tested. The ethanolic extract showed 42.10% anti-inflammatory effect at dose 500 mg kg-1, p.o. Preliminary phytochemical screening of the extract revealed the presence of alkaloids, saponin, glycosides, steroids and sterol. The results obtained in this study lend credence to the ethnomedical use of the plant in the management of pain and inflammatory conditions. Thus, supporting the development of the biologically active substances as analgesics and anti-inflammatory agents. M. charantia may therefore, be a good candidate for functional foods as well as pharmaceutics.
  Anik Barua , Rabiul Hossain , Parmita Banik , Rajia Sultana , Nurul Absar and Rashadul Hossain
  Background and Objective: Tinospora cordifolia (Willd.) Hook.f. is employed in Ayurvedic system of medicine for the treatment of diabetes, jaundice, rheumatoid arthritis, metabolic disorders and likewise utilized as memory enhancer. In this study it tend to analyze in vivo sedative and anxiety potential in mice for T. cordifolia stems extracted in methanol. Materials and Methods: The crude extract of T. cordifolia was evaluated for its central nervous system depressant effect using rodent behavioral models; such as ‘Hole cross test’ and ‘Open field test’ for its sedative properties and an ‘Elevated plus maze test’ for its anxiolytic potential. Results: In sedative study, the extract at a dose of 200 and 400 mg kg1 b.wt. showed a dose-dependent and statistically significant (p<0.05-0.01) suppression of motor activity and exploratory activity of the mice in both open field and hole cross test. The extract also showed increased percentage of entry into open arms at both doses in anxiolytic potential study. At a dose of 400 mg kg1 b.wt. maximum anxiolytic activity (p<0.001) was found which was comparable to the standard Diazepam. Conclusion: This study unconcealed that the methanolic extract of Tinospora cordifolia has significant central nervous system depressant impact. More studies on active constituent of the extract will give approaches for therapeutic intervention.
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