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Articles by Nurdin Rahman
Total Records ( 4 ) for Nurdin Rahman
  Nurdin Rahman , Nikmah Utami Dewi and Bohari
  Background and Objective: Antioxidants are a necessary nutrient component of the body to prevent and cope with oxidative stress. Avocado leaf allegedly has a natural antioxidant that can meet the needs of antioxidants which are still limited, especially for people with degenerative diseases. This study aimed to identify and analyze the phytochemical content and antioxidant power of avocado leaf extract. Materials and Methods: The type of research is pure experiment. The avocado leaf extraction preparation was macerated using 96% ethanol solvent with a ratio of 1:10 (w/v) for 3×24 h. Phytochemical types analyzed were flavonoids, saponins, polyphenols, tannins, alkaloids and steroids. Measurement of antioxidant activity using DPPH (1,1-Diphenyl-2-picrylhydrazyl) method on avocado leaf extract and vitamin C (control group). Data analysis was unpaired t-test, one-way ANOVA test and linear regression test with significant value was p<0.01. Results: Positive avocado leaf extract contains flavonoids, saponins, tannins and steroids. Antioxidant activity avocado starch extract (absorbance DPPH = 0.797) is strong with IC50 of 72.61 mg L–1 and vitamin C as positive control is also very strong with IC50 (mg L–1) of 23.03. Conclusion: Avocado leaf extract contains phytochemical substances with a strong antioxidant that can be used to prevent and cope with oxidative stress.
  Abdul Rahim , Gatot Siswo Hutomo , Nurdin Rahman , Bohari and Sukisman Abdul Halid
  Background and Objective: Arenga starch was extracted from the pith of sugar palm (Arenga pinnata), chemically modified by acetylation were produced acetylated arenga starches with different concentrations of acetic anhydride (4, 8, 12, 16% of starch basis). To evaluate the effect of acetylation on the structure and functional properties of chemical modified starches. Materials and Methods: The experimental research using material i.e., the arenga starch from the pith of palm sugar (Arenga pinnata), acetic anhydride 98%, NaOH, HCl, ethanol 96%, KOH 99.99%, H2SO4 96.1%, KBr, acetone and olive oil. Methods i.e., acetylation of arenga starch, determination of acetyl percentage and degree of substitution, fourier transform infrared (FTIR) spectra, X-ray diffraction, water and oil holding capacity, swelling power and solubility, crude fiber. Data were assessed by one-way analysis of variance and were carried out with Duncan’s multiple test (p<0.05). Results: The percentage of acetyl groups and degree of substitution increased with increasing in concentrations of acetic anhydride. Fourier transform infrared spectra of acetylated arenga starches additionally showed bands of varying intensity attributable to the acetyl groups introduced of the ester group in the sign to 1720.50-1728.22 cm–1. All starch granules were pattern of A-type crystallinity and relative crystallinity of acetylated arenga starches were lower than that native arenga starch. The water holding capacity, oil holding capacity, swelling power and fibre content of acetylated arenga starches increased but solubility decreased with the increasing in concentrations of acetic anhydride. Conclusion: Acetylated arenga starches were synthesized with acetic anhydride for use in food.
  Nurdin Rahman , Sri Mulyani Sabang , Nikmah Utami Dewi and Bohari
  Background and Objective: Preclinical testing of the use of avocado leaf extract for decreasing blood glucose level is still limited. This study aimed to analyze the effect of avocado leaf extract on fasting blood glucose level in male white rats. Materials and Methods: This study was a pre-experiment with six groups of pretest posttest with control group. The samples were male white rats (Rattus norvegicus) of Wistar strain, ±3 months old, with the treatment groups: Group 1: Feed+Streptozotocin (STZ)+10% sucrose+avocado leaf extract dose of 100 mg kg1 b.wt., Group 2: Feed+STZ+10% sucrose+avocado leaf extract dose 150 mg kg1 b.wt., Group 3: Feed+STZ+10% sucrose+avocado leaf extract dose 200 mg kg1 b.wt., Group 4: Feed+STZ+10% sucrose, Group 5: Feed+STZ+10% sucrose+glibenclamide and Group 6: Feed. Data analysis used ANOVA and paired t-test with p<0.05. Results: The early fasting blood glucose level of the white rats was 58-97 mg dL1 (p = 0.897). Giving STZ increases the fasting blood glucose level to 83-128 mg dL1 (p = 0.136). Meanwhile, giving avocado leaf extract on day 14 decreased 68-77 mg dL1 (p = 0.000). Group 2 experienced a significant decrease on day 7, which was 28.22 mg dL1 (p = 0.028) and day 14, which was 31.33 mg dL1 (p = 0.015). Conclusion: Avocado leaf extract with a dose of 150 mg kg1 b.wt. is effective in reducing the high fasting blood glucose level in white rats.
  Nurdin Rahman , Muhammad Ryman Napirah , Devi Nadila and Bohari
  Background and Objective: The high incidence of stunting is a serious problem for the government of Palu. Thus, a study of the determinants of stunting in Palu is necessary. This study aimed to assess potential modifiable risk factors that lead to stunting among children. Materials and Methods: This study used a case-control research design with a 1:3 ratio of cases (children who were stunted) to controls (children who were not stunted) and conducted from September, 2016-March, 2017. The population included all stunted children aged 7-24 months in Petobo village, Palu. The number of cases was 36 as obtained by the total sampling method and the number of control children was 108, who were selected randomly. Univariate, bivariate and multivariate with logistic regression analyses were used. Results: The determinants of stunting were family income (p = 0.000), exclusive breast feeding (p = 0.002), immunization status (p = 0.147), environmental sanitation (p = 0.001) and maternal age during pregnancy (p = 0.003). The multivariate analysis results showed that family income [odds ratio(OR) = 6.24] was the highest risk factor for stunting. Exclusive breast feeding (OR = 4.33), environmental sanitation (OR = 4.60) and maternal age during pregnancy (OR = 3.05) were associated with the same risk of stunting. Conclusion: In Petobo village, Palu, the main modifiable risk factor that leads to stunting among children is family income, followed by environmental sanitation, exclusive breast feeding and maternal age during pregnancy.
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