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Articles by Novitsky YA
Total Records ( 2 ) for Novitsky YA
  Masoompour SM , Bagheri MH , Borhani Haghighi A , Novitsky YA , Sadeghi B , Gharibdoust F , Larijani B and Ranjbar Omrani G
  Diabetes foot ulcers are a major predictor of future lower-extremity amputation in patients with diabetes. The animal studies have indicated that treatment with a new herbal extract named ANGIPARS™ improves healing of chronic ulcers. The main objective of the study was to evaluate the safety and healing rates of diabetic foot ulcers in patients treated with ANGIPARS™.
Ten diabetic patients (7 males and 3 females) were eligible for enrollment in this single arm before-after clinical trial. The target wound`s greatest length and width was measured at baseline. The target wound was photographed at baseline and then every two weeks. The wound area was determined by means of planimetry.
The mean age of patients was 57± 2.3 years. The mean surface area of ulcers was 12.32±11 cm2, 9.55±9 cm2, and 6.96±6 cm2 at baseline, one month and two months of study, respectivly. Our results showed that the drug could reduce the wound size at least 50% during 8 weeks period. We found no adverse side effects in our patients.
The main conclusion of the present study was to show the efficacy and safety of ANGIPARS™ as a novel therapy in diabetic foot ulcers.
  Shamimi Nouri K , Heshmat R , Karimian R , Nasli E , Larijani B , Novitsky YA , Farhadi M and Gharibdoust F
  The prevalence of pressure ulcers of the foot is a major health care problem in frail elderly patients. A pressure sore dramatically increases the cost of medical and nursing care, and effective treatment has always been an essential nursing concern. Management options for pressure ulcers include local wound care; surgical repair and, more recently, topical application of growth factors.
The main goal of this study was to examine the effects of intravenous treatment of Semelil (ANGIPARS™), a new herbal extract in patients with severe, noninfected pressure ulcers of the foot.
As a randomized clinical trial, 18 patients with pressure ulcers were recruited from Vali-e-Asr hospital, Medical Sciences/ University of Tehran, Iran. Nine patients received intravenous Semelil (ANGIPARS™) besides to conventional therapy and nine received only conventional treatment.
At the baseline, the treatment and control groups did not differ across demographic variables, clinical characteristics, and functional measures. The mean surface areas of the ulcers were reduced 43.2 ± 57.4 cm2 (80.3%) and 2.8± 6.2 cm2 (6.3%) in the treatment and control groups, respectively (p=0.000).
The average reduction in pressure ulcer area at four weeks was statistically and clinically greater in the treatment group than in the control group So, intravenous Semelil (ANGIPARS™) can be recommended as an effective treatment for patients with severe pressure ulcers.
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