Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the
coverage of the most important and influential journals
to meet the needs of the global scientific community.
The aim of this study was to determine the in vivo antioxidant activity of newly formulated Oil in Water (O/W) creams of methanolic extract of Cassia tora L. leaves. O/W creams of methanolic extract of Cassia tora L. leaves was prepared, evaluated and tested for acute dermal toxicity study. The different O/W creams showed good physical characteristics and pass the sensitivity, irritation, grittiness and bleeding test. Exposure of Ultraviolet-B (UV-B) light decreased the reduced Glutathione (GSH), Catalase (CAT) and Superoxide Dismutase (SOD) activities and increased the Lipid Peroxidation (LPO). The oxidative stress induced by exposure of UV-B light in rats was minimized by single dose topical application of different concentrations of O/W creams and Cassia tora Methanolic extract (CTM). Researchers concluded that topical O/W creams and methanolic extract of Cassia tora leaves has potent antioxidant activity.