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Articles by Nedret Kilic
Total Records ( 2 ) for Nedret Kilic
  Nedret Kilic , Yildiz Guney , Ayse Hicsonmez , Melike Erol , Ferhan Komurcu , Aysen Dizman , Ummuhani Ozel Turkcu and Meltem Nalca Andrieu
  It is aimed to examine the state of the oxidant-antioxidant system in the liver of guinea pig caused by ionizing radiation at two different dose levels in the early period. The research was carried out on guinea pigs irradiated with the doses of 8 Gy (group 2) or 15 Gy (group 3) (single dose/whole body) in comparison with control group (group 1). The levels of thioredoxin reductase (TR) in the kidney was measured. The results obtained by non-irradiated and irradiated (8 Gy and 15 Gy) kidneys on guinea pigs indicated that; in 8-15 Gy irradiated animal kidneys TR activity elevated significantly (p<0.001) when compared to the controls, but there was no difference between 8 Gy and 15 Gy irradiated animal groups. The data have shown that gamma-irradiation results in significant increase in TR activity at two different dose levels.
  Melike Erol Demirbilek , Nedret Kilic , H. Ferhan Komurcu and K. Okhan Akin
  The role of increased oxidative stress in the development of oxidative protein damage in aging have been reported. There is an important role of oxidative stress on development of dementia. Advanced oxidation protein products (AOPPs) are novel markers of oxidative stress. The aim of this study was to compare AOPP levels in healthy aged person and aged person with dementia. AOPP levels were in the control group 83.36 ± 35.51 ┬Ámol/L, and 178.78 ± 110.50 ┬Ámol/L in the group with dementia. This elevation in the group with dementia was statistically significant (p<0.05). AOPP might be a useful novel indicator of oxidative stress in dementia.
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