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Articles by Neda Nayebi
Total Records ( 2 ) for Neda Nayebi
  Shirin Hasani-Ranjbar , Somayeh Khosravi , Neda Nayebi , Bagher Larijani and Mohammad Abdollahi
  This review focuses on the efficacy and safety of medicinal plants which have been utilized in traditional medicine for anti-aging purpose. All relevant databases were searched for the terms “anti-aging” and “herbs” or “medicinal plant” without limitation up to 30th January 2011. All the clinical and non-clinical studies with the outcome of change in aging process were included. Search in databases resulted in 1733 articles that on the basis of inclusion/exclusion criteria, 67 studies were finally included. Six human and 61 animal studies were reviewed for the effect of anti-aging herbs on aging process. Most of the studies showed significant improvement in brain function (memory, cognitive, anxiety), sexual disorder and skin wrinkle. From the performed studies, the exact mechanism of anti-aging action and side effect cannot be concluded and thus further studies would be helpful.
  Shirin Hasani-Ranjbar , Neda Nayebi , Bagher Larijani and Mohammad Abdollahi
  This review focuses on the efficacy and safety of Teucrium species that are effective in the management of different conditions in human and animal. Embase, Scopus, Pubmed, Google Scholar and IranMedex databases were searched up to 11th May 2009. The search terms were Teucrium or germander or Calpoureh. All of the human and animal studies considered the effects of Teucrium with the key outcome of change in blood glucose, serum lipids, anti-oxidant parameters, hepatic enzymes, anti-inflammation, analgesic effects, anti-ulcer effects anti-microbial effect and toxic effects were included. Studies performed on cell lines, in vitro studies, reviews and letters to editors were excluded. Of initial search, 7325 record were reviewed for inclusion or exclusion in study. Finally, 68 studies were included. Some animal and one human study showed hypoglycemic effects of Teucrium. In one animal study, Teucrium decreased serum cholesterol and triglyceride in hyper-lipidemic rats. Some studies indicated anti-oxidant, anti-spasmodic, anti-nociceptive and anti-inflammatory properties of Teucrium. According to histopathological and biochemical evidences, high doses or long-term administration of Teucrium may induce progressive impairment of neuromuscular coordination and reversible or irreversible hepatic damage. Teucrium has antidiabetic effect by enhancing secretion of insulin from the pancreas. The flavonoids and sterols are responsible for the anti-inflammatory activity of this plant. Isolation and characterization of Teucrium constituents is suggested to reach suitable drugs.
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