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Articles by Nastaran Ranjbari
Total Records ( 2 ) for Nastaran Ranjbari
  Afshin Habibi , Nastaran Ranjbari , Fakher Rahim and Nematollah Jazayeri
  One of the most common cancers in the world, especially in underdeveloped countries, is Gastric Cancer (GC) which kills thousands of people annually. It is also prevalent in our country, Iran and according to statistics, it is the most common cancer in men. Since, the relationship between expression of CD34 cell surface markers and many cancers has been approved in the present study, the marker expression association with GC is studied. In this study, a total of 47 paraffin blocks of patients with GC referring to Imam Khomeini hospital in Ahvaz, during 2003-2013 were used. The mean age of 47 patients, including, 35 men (74.5%) and 12 women, was 60±16.05 years old ranging from 24-84. The mean tumor size was 34.5 ranging from 2-12 cm. More than 71% of tumors were intestinal type and the depth of more than 74% of them was in T3 phase. Incidence of marker was positive in only 8 patients (17%) and in rest 39 was negative. The CD34 expression was significantly correlated only with the tumor type (p = 0.00), degree of malignancy (p = 0.00) and neural invasion (p = 0.01). In this study, a positive correlation was observed between the marker expression and three factors of tumor type, degree of differentiation and neural invasion. It was also concluded that due to the negative CD34 expression in 83% of samples, the absence of positive CD34 cells in tumor tissue can be considered as a marker in GC, although it is recommended to do further research with more samples in this context.
  Nastaran Ranjbari , Fakher Rahim , Kambiz Masoumi and Firoozeh Kahkeshpuor
  Fine Needle Aspiration (FNA) is a relatively painless, safe and inexpensive diagnostic method, which is a widely accepted for the diagnosis of salivary glands neoplastic and inflammatory lesions before surgery. The aim of this study was to evaluate the diagnostic value of FNA in the diagnosis of salivary gland tumors nature compared with the histopathological results after mass excision. This is a cross-sectional study, where since April 2009 to March 2012, all patients complaining about salivary gland tumors referred to the ear, nose and throat ward of Ahvaz Imam Khomeini hospital and undergone FNA and biopsy have been studied. Then, the results of FNA were compared with pathology results after mass excision, as well as the diagnostic accuracy of FNA was calculated. In this study, 160 patients were studied including 88 females (55%) and 72 males (45%). Most patients were in the age group of 31-40 years and lowest in patients aged over 80 years. The mean age of patients was 41.7±18.9 with a minimum 3 years and the maximum was 85 years old. The FNA sensitivity in salivary gland tumor to pathological findings after mass excision was calculated 92.3% and its characteristics 99%. The positive predictive value was 96% and negative predicted value 97.9%. As shown in this study, FNA sensitivity has a high specificity and diagnostic value in the detection of the salivary gland lesions. Given that it is an inexpensive, safe and reliable method, it is recommended to be used more widely.
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