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Articles by N.K. Mahajan
Total Records ( 2 ) for N.K. Mahajan
  Sunil K. Mor , G. Narang , N. Jindal , N.K. Mahajan , P.C. Sharma and N.K. Rakha
  The epidemiological data of Infectious Bursal Disease (IBD) in 483 broiler chicken flocks were analyzed from July, 2005 to June, 2008. Overall morbidity, cumulative mortality and case fatality rate due to the disease were recorded as 4.54, 2.34 and 51.69%, respectively. Of the total IBD-affected flocks, 192, 211, and 80 flocks were affected during the years 2005-06, 2006-07 and 2007-08, respectively. Dullness, depression, anorexia, ruffled feathers and inability to move were evident in almost all the IBD-affected flocks. The affected birds had yellowish white or greenish yellow diarrhoea. At necropsy, the gross lesions were observed mainly in bursa of Fabricius followed by changes in thigh and breast muscles. The disease was recorded throughout the year. Maximum cases (52.80%) were observed in birds of 21-30 days of age followed by 33.13% in the age group of 31-40 days. Although the disease was observed in both IBD-vaccinated (334) and unvaccinated (149) flocks, percent morbidity and cumulative mortality were higher in unvaccinated flocks than in the vaccinated flocks. Factors like improper vaccination, poor biosecurity measures and existence of very virulent strains of IBD virus could be the reasons for disease in the vaccinated flocks. Continuous surveillance may help in better understanding of the epidemiology of infectious bursal disease virus in broiler chickens in this region.
  V. Gowthaman , S.D. Singh , K. Dhama , R. Barathidasan , M. Asok Kumar , P.A. Desingu , N.K. Mahajan and M.A. Ramakrishnan
  Adenoviruses have been isolated from both clinically healthy and diseased birds worldwide. The pathogenic role of most of the FAdVs is still questionable. They can quickly take on the role of opportunistic pathogens when additional factors, particularly concurrent infections, adversely affect the health of the avian host. Immnosuppressing agents especially chicken infectious anemia and infectious bursal disease viruses are known to enhance the pathogenicity of FAdVs upon coinfection. The aim of the present study was to screen for the involvement of FAdV in poultry flocks affected with respiratory disease complex by RT-PCR. The samples were also screened by RT-PCR/PCR for other respiratory pathogens. Thirty two commercial poultry flocks with the history of respiratory disease complex from various parts of India. FAdV nucleic acid could be detected in tissue samples of 13 out of 34 farms investigated. Out of 13 FAdV positive farms, FAdV and CIAV were alone detected in 4/13 (31%) whereas, in other farms more than two respiratory pathogens were detected together. CIAV was detected in all the farms (34/34) investigated. Eosinophilic intranuclear inclusion bodies were noticed in FAdV infected laryngeal and tracheal epithelium under light microscopy. The findings of the study assert that FAdV can play the role of primary respiratory pathogen in immunocompromised birds and also in the presence of other respiratory pathogens.
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