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Articles by Mustafa Mansur TATLI
Total Records ( 3 ) for Mustafa Mansur TATLI
  Mustafa Mansur TATLI , Ahmet KARADAG , Ender ODEMIS , Sumeyye SARRAOGLU and Mehmet YORUBULUT

Aim: Magnetic resonance imaging (MRI) is widely used in the diagnosis of acute bilirubin encephalopathy, but the relationship between MRI findings and neurodevelopmental outcome in newborns with acute bilirubin encephalopathy remains unclear. The aim of this study was to investigate the relationship between acute bilirubin encephalopathy, MRI findings, and neurodevelopmental outcome.

Materials and Methods: The study included 13 infants with acute bilirubin encephalopathy. MRI was performed at 11-30 days of age. Infants were evaluated using the Denver Developmental Screening Test at 3 and 6 months of age.

Results: Four of the 13 infants developed well. Five infants had abnormal MRI findings. Two of these 5 infants had good neurodevelopmental outcome. Nine of the 13 patients had poor developmental outcomes.

Conclusion: In newborns with acute bilirubin encephalopathy, neither encephalopathy stage nor MRI findings predicted neurodevelopmental outcome, as measured by the Denver Developmental Screening Test.

  Alparslan Tonbul , CŁneyt Tayman , Ahmet Karadag , Halise Akca , Nurdan Uras and Mustafa Mansur Tatli
  Aim:To determine the fluid requirement of small-for-gestational-age (SGA) newborns and to compare them with that of appropriate for gestational age (AGA) newborns in the first 5 days of life.
Materials and methods: The present study was conducted from January 2007 to August 2007, including newborns with a gestation age of 32-40 weeks, with respiratory problems, feeding problems, and prematurity, and required intravenous fluid for at least 3 days. Two study groups were established: SGA (group 1) and AGA (group 2) according to the Lubchenco scale. All newborns were cared at an ambient humidity of 40% in an incubator and received intravenous fluid therapy. Daily fluid intake was adjusted with urine output, hydration, and weight gain/loss.
Results: During the study period, 124 newborns were admitted to neonatal wards, and only 48 newborns met the inclusion criteria. Two study groups were formed: group 1, SGA (n = 24) and group 2, AGA (n = 24). The comparison of percentage weight loss differences on day 5 with birth weight was 1.39 ± 3.7% in group 1, and 4.29 ± 4.02% in group 2. The mean percentage of weight loss in group 1 was lower than group 2 (P = 0.014). During 5 days, the mean daily fluid requirements in groups 1 and 2 were measured as 103.18 ± 28.68 cc/kg per day and 129.09 ± 25.8 cc/kg per day. The daily fluid requirement in group 1 was lower compared to group 2 (P = 0.003).
Conclusion: SGA newborns need lower fluid requirements, and experience lower weight loss during the first 5 days of life as compared with AGA counterparts, which suggests that fluid requirement of SGA newborns are different from AGA newborns and the fluid therapy of SGA newborns should be special.
  Ozlem KIRMEMIS , Mustafa Mansur TATLI , Cuneyt TAYMAN , Cemile KOCA , Ahmet KARADAG , Nurdan URAS , Ugur DILMEN and Hasan KAFALI
  Aim: To test the hypothesis that serum S100B levels could be useful in detecting neurological damage in infants with intrauterine growth retardation (IUGR). Materials and methods: The study group consisted of infants with IUGR and the control group consisted of age-matched healthy infants. S100B protein levels were measured after birth and compared between groups. Results: For this study, 43 infants with IUGR and 25 infants as a control group were recruited. Gender, gestational age, type of delivery, and maternal age of the groups were statistically insignificant, with the exception of the mean birth weights (2120 ± 450 g in the IUGR group and 3096 ± 570 g in the control group (P < 0.001), respectively). S100B protein levels of the IUGR infants (1.13 ± 0.54) were significantly higher than those of the control group (0.45 ± 0.13) (P < 0.001). IUGR infants treated with antenatal steroids showed lower S100B levels than IUGR infants that did not receive antenatal steroid treatments (P < 0.05). The study group infants were divided into 2 groups, for growth retardation (GR) that was asymmetric (n = 15) and symmetric (n = 28). The asymmetric and symmetric GR infants’ S100B levels were 1.14 ± 0.47 pg/mL and 1.21 ± 0.34 pg/mL, respectively, and no significant differences were found between the 2 groups in terms of S100B levels (P = 0.32). Conclusion: The results of this study favor the opinion that there is an existing intrauterine hypoxia causing hypoxic brain tissue damage in IUGR infants, even when followed up with modern obstetrical screening protocols. Measurements of S100B may be useful in the prediction of outcome in these infants.
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