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Articles by Mostafa I. Waly
Total Records ( 3 ) for Mostafa I. Waly
  Mostafa I. Waly and Nejib Guizani
  Aluminum (Al) is an environmental toxin that induces oxidative stress in neuronal cells. Mushroom cultivar extract (MCE) acted as a potent antioxidant agent and protects against cellular oxidative stress in human cultured neuronal cells. This study aimed to investigate the neuroprotective effect of MCE against Al-induced neurotoxicity in rat brain. Forty Sprague-Dawley rats were divided into 4 groups (10 rats per group), control group, MCE-fed group, Al-administered group and MCE/Al-treated group. Animals were continuously fed ad-libitum their specific diets for 4 weeks. At the end of the experiment, all rats were sacrificed and the brain tissues were homogenized and examined for biochemical measurements of neurocellular oxidative stress indices [glutathione (GSH), Total Antioxidant Capacity (TAC), antioxidant enzymes and oxidized dichlorofluoresceine (DCF)]. Al-administration caused inhibition of antioxidant enzymes and a significant decrease in GSH and TAC levels, meanwhile it positively increased cellular oxidized DCF level, as well as Al concentration in brain tissues. Feeding animals with MCE had completely offset the Al-induced oxidative stress and significantly restrict the Al accumulation in brain tissues of Al-administered rats. The results obtained suggest that MCE acted as a potent dietary antioxidant and protects against Al-mediated neurotoxicity, by abrogating neuronal oxidative stress.
  Ghazi Daradkeh , Musthafa M Essa , S. Samir Al-Adawi , Roopa P. Koshy , Abdullah Al-Asmi and Mostafa I. Waly
  The elderly population is increasing worldwide and it has been suggested that senior citizens will continue to constitute the bulk of the population in many countries. Nutritional status of senior citizens are adversely affected by their frailty, chronic condition and declining cognitive functioning. Conversely, malnourished elderly further deteriorate their frailty, chronic disease and cognitive functioning. The aim of this review article is to recognize the importance of nutritional assessment of elderly population particularly those with cognitive impairment. First part is to highlight characteristic cognitive impairment among senior citizens and the second one highlight t he background in which malnutrition is a factor that leads to increased risk of morbidity and mortality in the elderly. This review also highlight salgorithms for safeguarding nutritional status among senior citizen and focuses on importance of nutritional screening, assessment and early intervention for safeguarding further deterioration of elderly who are likely to prone to cognitive impairment.
  Amanat Ali , Khalid M. Al-Zuhaibi , Mostafa I. Waly , Ahmed A. Al-Alawi , Jamal N. Al-Sabahi and Devarajan Sankar
  The study evaluated the chemical composition, fatty acids contents and Glycemic Index (GI) of two different types (white and black) of Omani halwa. Representative samples of Omani halwa were collected from the local market. The proximate composition and energy contents of white and black halwa did not vary significantly (p<0.05). The percentage moisture, crude protein, total fat, ash, crude fiber and Nitrogen Free Extract (NFE) in white and black halwa were 11.8 and 12.1; 0.28 and 0.44; 13.8 and 12.4; 0.01 and 0.02; 0.15 and 0.05 and 74.0 and 75.0, respectively. The energy values in white and black halwa were 421.3 and 413.4 kcal/100 g, respectively. No significant (p<0.05) differences were observed in the total fatty acids, Saturated Fatty Acids (SFA), Monounsaturated Fatty Acids (MUFA) and Polyunsaturated Fatty Acids (PUFA) content in both types of Omani halwa. The SFA were present in highest concentration. The proportionate percentages of SFA, MUFA and PUFA in white and black halwa were 64.57, 65.47, 31.28, 30.79, 4.11 and 3.74%, respectively. The average GI and GL values for white and black halwa also did not vary (p<0.05) and were 54.8 and 52.0 and 14 and 13.4, respectively. Although the glycemic index values of Omani halwa fall in low GI category (<55), it should be consumed with caution because of its high fat, in particular of SFA and high sugar contents.
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