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Articles by Mostafa I. Waly
Total Records ( 4 ) for Mostafa I. Waly
  Mostafa I. Waly , Amanat Ali , Yahya M. Al-Farsi , Neeru Bhatt , Hashim Al-Kilani , Allal Ouhtit and Masoud Y. Al-Maskari
  Leptinemia is associated with obesity and obesity and hyperinsulinemia are considered as the main etiological factors for type 2 diabetes mellitus (T2DM) among adult subjects. The present case-control study evaluated the dietary pattern and biochemical profile of newly diagnosed T2DM obese Omani adults as compared to their age, weight and gender matched control subjects. Two hundred Omani adults (100 obese adults newly diagnosed with T2DM and 100 healthy controls) were included in this study. Dietary intake, body mass index and biochemical measurements for fasting serum glucose, insulin, leptin and blood glycated hemoglobin levels were evaluated for all study participants. Subjects with T2DM showed significantly (p<0.05) higher daily intake of total fats, carbohydrates and energy as compared to controls. Leptinemia and hyperinsulinemia were common among obese diabetic adults as compared to controls. The mean fasting serum levels of glucose and glycated hemoglobin in obese diabetic subjects were significantly (p<0.05) higher than controls. Serum leptin level was found to be positively correlated with body mass index, serum insulin level and total energy intake in all the study subjects. Our results suggest that leptinemia is a risk factor for T2DM in obese Omani adults.
  Nejib Guizani and Mostafa I. Waly
  Hydrogen peroxide is an oxidative stress agent that is associated with depletion of intracellular glutathione and inhibition of antioxidant enzymes in different cell lines. Consumption of antioxidant-rich foods reduces cellular oxidative stress and its related health problems. This study aimed to assess the antioxidant properties of mushroom, Agaricus bisporous cultivar extract, against hydrogen peroxide induced oxidative stress in cultured human hepatic (HepG2) and neuronal (SH-SY5Y) cells. In this study, hydrogen peroxide caused significant oxidative stress in HepG2 and SH-SY5Y cells as demonstrated by glutathione depletion, impairment of total antioxidant capacity and inhibition of antioxidant enzymes (glutathione peroxidase, catalase and superoxide dismutase). Agaricusbisporous extract ameliorated the observed hydrogen peroxide-induced oxidative cellular insult as indicated by restoring the activity of glutathione and the assayed antioxidant enzymes to control levels. The results suggest that mushroom extract as antioxidant properties and protects against the oxidative stress induced by hydrogen peroxide-in cultured human hepatic and neuronal cells.
  Amanat Ali , Muhammad S. Al-Siyabi , Mostafa I. Waly and Hashem A. Kilani
  Despite the importance of physical activity and training, the optimum nutrient intake and good nutritional knowledge have been recognized as important factors in improving the athletic performance and health status of athletes. The present study was conducted to assess the nutritional knowledge, dietary habits, nutrient intake and nutritional status of Sultan Qaboos University student athletes. A cross-sectional study design was used to achieve the objectives. Seventy one (49 male and 22 female) student athletes with a mean age of 21.0±1.81 and 19.32±0.72 years and body mass index (BMI) of 22.51±1.98 and 20.34±2.97 kg/m2 for male and female respectively, participated in study. All subjects were interviewed in person. The study questionnaire consisted of questions related to demographic information, nutritional knowledge and a 7-days food diary to identify nutrient intake, food frequency and variety of food consumption. Significant differences (p<0.05) were observed in the main sources of nutrition information used by the male and female athletes. The male subjects had most of the nutrition information from friends (17%) as compared to female subjects who relied on the family members (20%). Significant (p<0.05) differences were also observed in nutritional knowledge and dietary habits scores of male and female athletes (57 and 49%, respectively). Male athletes were classified to have fair nutritional knowledge and dietary habits, whereas the female athletes had poor nutritional knowledge and dietary habits. Mean daily energy (2595±358 kcal/day) as well as the macronutrients intake in male student athletes was within the recommended dietary intake allowance. Study identified some gaps in nutritional knowledge, dietary habits and barriers in physical activity among student athletes and suggests a need for developing strategies in counseling and teaching of athletes to improve their athletic performance and health promotion.
  Amanat Ali , Khalid M. Al-Zuhaibi , Mostafa I. Waly , D. Sankar and Eugene H. Johnson
  Omani halwa is a traditional sweet delicacy. The present study evaluated the effects of feeding different levels of Omani halwa on the growth performance, fasting plasma glucose, glycated hemoglobin (HbA1c) and plasma lipid profile of Sprague-Dawley rats. Forty two, 4 weeks old male SD-rats were randomly divided into 7 groups containing 6 rats in each. Six experimental diets, (in which the normal rat chow was replaced with either white or black Omani halwa at 10, 15 and 20% level), were prepared and fed for 10 weeks. The group fed on rat chow acted as control. No significant (p<0.05) differences were observed in the feed consumption and growth performance of rats fed diets containing different levels and types of halwa. Significant (p<0.05) differences were observed in fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) values in rats fed different experimental diets. Diets containing 20% of halwa showed significantly (p<0.05) higher FPG and HbA1c values. Similarly the rats fed diets containing 20% of halwa showed significantly (p<0.05) higher lipid profile i.e., TC, TG, HDL-C and LDL-C values as compared to control. However, the TC/HDL-C ratio did not differ significantly (p>0.05). The plasma creatinine levels differed significantly (p<0.05) whereas the plasma albumin levels did not differ (p>0.05) in rats fed various experimental diets. Feeding Omani halwa at 15% level in diets did not affect (p>0.05) the growth, fasting plasma glucose, glycated hemoglobin (HbA1c) and lipid profile of rats.
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