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Articles by Morteza Pirali-Hamedani
Total Records ( 1 ) for Morteza Pirali-Hamedani
  Mohsen Amini , Morteza Pirali-Hamedani , Hossein Ali Ebrahimi , Majid Darabi and Abbas Shafiee
  A HPLC method for determination of rofecoxib in human serum was presented. The method is based on pre-column derivatization of analyte to a phenanthrene derivative of drug. Rofecoxib and internal standard were extracted from serum using liquid-liquid extraction. Upon exposure to UV light, drug was found to undergo a phtocyclization reaction giving a species with high absorbance. Validation of the method has been studied in the concentration range of 2-100 ng mL-1.
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