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Articles by Monsefi Malihezaman
Total Records ( 2 ) for Monsefi Malihezaman
  Monsefi Malihezaman , Mokhberi Mahbobe and Shams Lahijani Maryam
  Zataria multiflora Boiss (ZmB) and Elaeagnus angustifolia (Ea) are used in traditional folk for stomach tonic. Many pregnant women take these plants to treat the digestive problem that is natural during pregnancy. There were no any reported about the effects of these plants in adult and fetus stomach. In order to investigated the probably effects of theses extracts on the fetus digestive system, 28 pregnant BALB/c mice were divided into control, Sham and experimental groups that treated with 200 mg kg•1 aqueous extract of ZmB and 640 mg kg•1 aqueous extract of Ea from 6th to 15th days of pregnancy. The sham group was gavaged with equal amount of distilled water while the control group did not have any treatment. Pregnant mice were sacrificed in 16th day of pregnancy and the fetuses were extracted and their Crown-Rump lengths and weights were measured. Seven fetuses from different mothers were selected and transverse serial sections of their stomach were prepared. The volumes of different layers of stomach were estimated by Cavalieri method. The epithelial and muscular cells of stomach were studied under transmission electron microscopy. There were no significant differences on the volume of stomach after treatment by ZmB but Ea increased the volume of different layers of stomach. No significant differences revealed for weight and CRL of the fetuses. The number of mitochondria of epithelial cells and RER in smooth muscle cells were increased in experimental groups. We concluded that these plants are nonpathogenic and safe and reinforcer for fetuses stomach.
  Monsefi Malihezaman and Pahlavan Sara
  Involvement of men in control of population is lesser than women that may be due the limited contraceptive choices. For this purpose, the infertility effect of plants such as Anethum graveolens (L.) that used in folk remedy to decrease male fertility have been tested in animal models. Thirty adult male Wistar rats were divided into 3 groups of treatment group I, 70 mg kg-1, treatment group II, 100 mg kg-1 of aqueous extract that received in a volume of 1 mL by gavage daily for 32 days and control group were treated with 1 mL of distilled water. Body weights of all animals were recorded before and after of experiment. Serum testosterone levels at the beginning and the end of the experiment were measured. The animals were sacrificed and left testis, epididymis, seminal vesicle and prostate were dissected out and weighted. Sperm count, motility and nuclear maturity were examined. After tissue preparation of testis, seminiferous tubular diameter were measured and frequency of stages. After tissue preparation of testis, seminiferous tubular diameter were measured and frequency of stage of the the germinal epithelium cycle of seminiferous tubules were evaluated by using staging map. The treatment did not affect body and organ weight, serum testosterone levels, sperm count, motility and nuclear maturity from that of the control group. Spermatogenic cycle in seminiferous tubules and seminiferous tubular diameter did not altered by the treatment. These results suggest anti fertility effect for Anethum graveolens seed aqueous extract in rats at levels of 70 and 100 mg kg-1.
 
 
 
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