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Articles by Monica Nainta
Total Records ( 2 ) for Monica Nainta
  Monica Nainta and H.S. Banyal
  Humoral response exhibited by a fraction of Plasmodium berghei is evaluated in the present study. Immunization of mice with S fraction (supernatant of 20,000 rpm centrifugation) of Plasmodium berghei exhibited high humoral immune response. S fraction contained proteins of molecular weight ranging from 23.15-205.00 kDa. The humoral response was serodiagnostically analyzed employing ELISA, IFA and in vitro invasion inhibition assays. Antimalarial antibodies significantly inhibited invasion of Plasmodium berghei in short-term invasion assay. From the in vitro culture study it was found that S fraction exhibits a high humoral response and sera of five out of ten immunized mice inhibited more than 50% of invasion of erythrocytes by P. berghei.
  H.S. Banyal , Amit Tandon and Monica Nainta
  Extracts of tuber, leaves and fruits from Arisaema jacquemontii Bl. (Himalayan or Jacquemont’s cobra lily) were evaluated for their antimalarial properties against Plasmodium berghei (NK-65) maintained in white Swiss mice, Mus musculus (BALB/c). Peter’s 4 day test was employed and animals were administered to ethanol prepared extracts of plant parts orally. Extracts significantly inhibited multiplication of Plasmodium berghei. Tuber extract inhibited about 70% propagation of parasite followed by leaves and fruit while no parasite was seen in the smears of chloroquine treated mice.
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