Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
Articles by Mona H. Elsayad
Total Records ( 1 ) for Mona H. Elsayad
  Mona H. Elsayad and Mohammad A. Al-Kazzaz
  Background and Objective: Schistosoma mansoni (S. mansoni ) worms inhabit the portal triad which may affect the blood elements. The present study investigated the ameliorative effects of Nitazoxanide (NTZ) on some biochemical parameters in S. mansoni-infected mice. Materials and Methods: Swiss albino mice (n = 42) were used in this study and were divided into three groups. G1was normal (n = 6), 36 mice were infected with 100 S. mansoni cercariae were classified into two groups, G2 infected control group given only the vehicle (n = 18) and G3 was infected and treated with NTZ at a dose of 100 mg kg–1 for 7 days (n = 18). Treatment started 7 weeks’ post-infection by oral route. Blood samples were collected at 1, 2 and 4 weeks post treatment to obtain serum for liver functions (ALT, AST and ALP), kidney functions tests (blood urea and serum creatinine) and cholinergic function (serum cholinesterase level). Results: NTZ decreased significantly the elevated levels of liver enzymes, urea and creatinine in treated mice at 1, 2 and 4 weeks post treatment (WPT). NTZ caused significant elevation in the level of AChE at 2 and 4 WPT. Conclusion: Nitazoxanide was not only drastic but also showed some corrective action in biochemical parameters in S. mansoni-infected mice.
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility