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Articles by Mojgan Gharipour
Total Records ( 3 ) for Mojgan Gharipour
  Ali Roshan , Mojgan Gharipour , Hosein Khosravi Boroujeni , Gholam Reza Sharifzadeh and Hojat Rohi
  The impact of different nutritional regimens on long-term prognosis and outcome in diabetic patients with Coronary Artery Disease (CAD) is questioned. The objective of the present study was to determine the effects of different nutritional components of Mediterranean regimen on long-term cardiovascular events in diabetic patients with CAD in Iranian population. In a prospective cohort study, researchers recruited 233 consecutive patients with the diagnosis of type 2 diabetes mellitus for at least 6 months with documented CAD. Nutritional assessment was obtained by a validated semi-quantitative Food Frequency Questionnaire (FFQ) and the diet score was calculated on the basis of Mediterranean Diet Quality Index (Med-DQI). For assessing long-term CAD prognosis, the patients were followed by telephone for 1 year. The study endpoint was long-term MACCE (defined as occurrence of one of these morbidities including death, non-fatal myocardial infarction or need to revascularization). About 1 year death was revealed in 19 (8.2%). The 2 patients (0.9%) suffered non-fatal myocardial infarction and 14 (6.0%) needed to revascularization within 1 year after discharge from hospital. Overall, 1 year MACCE in study population was 12.4%. There were significant relationships between death rate and dietary scores of saturated fatty acid, cholesterol, meats, fish and fruit and vegetables. Also, significant relationships were found between MACCE rate and dietary scores of saturated fatty acid, cholesterol and fruit and vegetables. Mediterranean dietary regimens including low level of cholesterol and saturated fatty acid can effectively improve long-term outcome, including 1 year death and MACCE in diabetic patients with CAD.
  Majid Kolahdouzan , Mojgan Gharipour and Behnaz Nikkar Esfahani
  Advantages or disadvantages of calorie restriction as a factor for reducing Coronary Artery Disease (CAD) risk factors have been questioned. In the present study, researchers examined the effects of a short-term dietary calorie intake on laboratory parameters related to the risk factors for CAD, especially serum creatinine rise in patients with CAD. In a cross-sectional study, 444 consecutive patients with the diagnosis of CAD and candidate for coronary artery bypass surgery were participated in this study. Laboratory parameters as CAD risk factors were measured. Energy intake was estimated from the self recorded dietary intake records so that the energy content of the entire diet is computed as the sum of the energy available in each food item consumed. Linear regression analysis showed no significant relationships between dietary energy intake and laboratory parameters of fasting blood glucose, lipoprotein and lipid profiles, however in both obese and non-obese groups, there were adverse relationships between dietary energy intake and last serum creatinine. In mutivariate analysis, after adjusting for confounders, significant adverse relationship was found between dietary energy intake and serum creatinine concentration.
  Hojjat Rouhi-Broujeni , Esfandiar Heidarian , Pariya Darvishzadeh-Boroojeni , Mahmoud Rafieian-Kopaei and Mojgan Gharipour
  Hyperlipidemia is the most important cardiovascular risk factor. Moringa peregrina is traditionally used as antihyperglycemia and antihyperlipidemia. This study aimed to investigate, the effects of hydroalcoholic extract of Moringa peregrina on lipid profile and atherogenic biomarkers of hyperlipidemic rat. In this experimental study, 40 male Wistar rats were divided into four equal groups: Normal rats, high fat diet rats (hyperlipidemia induced with persintra-M) high fat diet with Moringa peregrina, high fat diet plus atorvastatin. The regimens were given orally (by gavage) for 40 days. Also, serum lipid profile, thiol level, Malondyaldehide (MDA), antioxidant capacity, ferritin, CRP as well as atherogenic index were determined. Treatment with Moringa peregrina seeds significantly decreased serum LDL, VLDL, trigeliceride and total cholesterol and increased HDL-C. The Atherogenic index decreased. Also, MDA, ferritin and CRP were reduced and plasma thiol level icreased. The data demonstrates that the leaves ethanolic extract of Morninga peregrina has antioxidant activity and antilipidemic effect on hyperlipidemic rats. Also, reduction of lipid and protein peroxidation as an index of oxidative stress is evident.
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