Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
 
Articles by Mohsen Rezaei
Total Records ( 1 ) for Mohsen Rezaei
  Jalal Pourahmad , Niloofar Rezvani , Mohsen Rezaei and Abolhasan Ahmadiani
  In this study we examined the intra and extracellular glutathione levels in both glial cells and hepatocytes of rats during continuous pain induction. Animals were divided in 4 groups; one day, four day and seven day pain groups vs. control group. Results showed that the maximum generation of ROS occurs in four day group of continuous pain induction in both glia and hepatocytes of rats. The intracellular GSH was at highest level in one day pain group due to GSH influx and synthesis as two defensive mechanisms against oxidative stress in both glia and hepatocytes. In hepatocytes, however, by considering the levels of extracellular GSSG in one day pain group, it seems that the enzymatic function of GSSG reductase is also another important defense mechanism in the first group of continuous pain induction. Maximum extra cellular GSSG was in 7 day pain group in both glia and hepatocytes. Results suggest that following continuous pain induction, oxidative stress is the major cause for GSH depletion in both glia and hepatocytes and leads cells to the later consequences including apoptosis.
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility