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by
Mohammad Farhan Qureshi |
Total Records (
2 ) for
Mohammad Farhan Qureshi |
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Mohammad Farhan Qureshi
,
Mohammad Al Bakrah
and
U. Venkatramana Shenoy
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This is a study of 20 cases of Wilms` tumor studied over a period of 3 years covering different hospitals of Karnataka in India. Although the study was concluded in the year 2000, it was found worthwhile to demonstrate that inclusion of the results of advance researches can improve the management of Wilms` tumor. This is to highlight the bitter realities that the little patients succumb to harsh disease just because the facilities of research developments do not reach the hospitals. The presentation of our study would show if the modern researches on (i) expression of genes and receptors (ii) immunological assays (iii) microarray technology would have been available, there would have been reduction in mortality. In this study during the last three years of 2000, the patients were studied in detail by taking history and clinical examination. Specific investigations like ultrasound of the abdomen, FNAC, CT scan, in addition to routine investigations were carried out. Treatment modalities included surgical treatment like nephrectomy, partial nephrectomy, chemotherapy and radiotherapy depending on the staging. The results of this study showed that (i) the stage I and II cases have good prognosis if detected early and managed aggressively (ii) that CT scan did not show any superiority over ultrasound evaluation except for the fact that it delineated internal characters of the tumor better (iii) Surgery could be performed successfully in all patients without any morbidity and mortality and (iv) Wilms` tumor responds very well to combination chemotherapy. However; recurrence, toxicity and mortality were difficult to be avoided. It is suggested that World Health Authorities may take a decision to implement the developments in researches for clinical management of Wilms`tumor to farthest hospitals in any country. |
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Abdurrahman Al Diab
,
S. Qureshi
,
Khalid A. Al Saleh
,
Farjah H. Al Qahtani
,
Aamer Aleem
,
Mohammad Farhan Qureshi
,
Viquar Fatima Qureshi
and
Mohammad Rehan Qureshi
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Literature reports suggest a tremendous decline in the global incidence, mortality and morbidity of Colorectal Cancer (CRC) during the post-millennium as compared to the pre-millennium. These developments are attributed to the advancement in technicalities and researches. The status of CRC in the Kingdom of Saudi Arabia (KSA) during the pre-millennium restricted to most of the etiological, histological and epidemiological researches while progress around the world had already begun studies on molecular level. During the third millennium, there are active genome level researches in addition to the development of the link of MicroRNAs with progression of cancer. Although, research on gene expression began in KSA but its involvement in the discovery of newer compounds is still a vision. Furthermore, the researches in KSA lag behind in the new developed era of MicroRNAs. This review on the development of research activities on CRC has revealed that researches in KSA are slow and late but do not lag behind in the global scientific maneuvers taking place in the third millennium. |
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